LRRK2
Leucine-rich repeat kinase 2 (LRRK2 or RIP7) is a member of the receptor-interacting protein kinase family. It is a large multidomain protein kinase that includes leucine-rich repeats and a GTPase domain. Mutations in LRRK2 are commonly associated with late-onset Parkinson's disease (PD). LRRK2 is also known as dardarin.
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GSK2578215A
Catalog No. A12798 LRRK2 kinase 抑制剂GSK2578215A是一种有效的富含亮氨酸的重复激酶2(LRRK2)抑制剂(LRRK2 [G2019S]突变体和野生型LRRK2的IC50值分别为8.9和10.1 nM)。 了解更多 -
GNE 9605
Catalog No. A14149 -
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PF-06371900
Catalog No. A17221 LRRK2 inhibitorPF-06371900 is a potent and highly selective leucine rich repeat kinase 2 (LRRK2) inhibitor. 了解更多 -
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PFE-360 (PF-06685360)
Catalog No. A18816 LRRK2 inhibitorPFE-360, also known asd PF-06685360, is a potent and selective inhibitor of LRRK2 kinase. 了解更多 -
GNE-7915
Catalog No. A13748 -
CZC-25146 hydrochloride
Catalog No. A13448 -
LRRK2-IN-1
Catalog No. A11477 -
PF-06447475
Catalog No. A15504 LRRK2 抑制剂PF-06447475是一种高效,选择性,脑渗透性LRRK2抑制剂,对Wt LRRK2/G2019S LRRK2的IC50分别为3 nM/11 nM。 了解更多 -
CZC54252 hydrochloride
Catalog No. A15510 LRRK2 抑制剂CZC54252 hydrochloride是一种有效的LRRK2抑制剂,野生型和G2019S LRRK2的IC50分别为1.28 nM和1.85 nM。 了解更多