产品详情
LY 3200882是有效的、高选择性TGF-β receptor type 1 (TGFβRI)抑制剂,在体外肿瘤组织和免疫细胞以及体内皮下肿瘤中,有效地以浓度依赖方式抑制TGFβ介导的SMAD磷酸化。
In vitro | DMSO | 79 mg/mL (181.39 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 22.96 mL | 114.81 mL | 229.61 mL |
0.5 mM | 4.59 mL | 22.96 mL | 45.92 mL |
1 mM | 2.3 mL | 11.48 mL | 22.96 mL |
5 mM | 0.46 mL | 2.3 mL | 4.59 mL |
*The above data is based on the productmolecular weight 435.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A16816 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 435.52 |
Formula | C24H29N5O3 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1898283-02-7 |
Synonyms | LY-3200882, LY3200882 |
SMILES | CC(O)(C)C1=NC=CC(NC2=NC=CC(OC3=CN(C4CC4)N=C3C5CCOCC5)=C2)=C1 |
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