产品详情
LY2835219 (abemaciclib)是一种细胞周期蛋白依赖性激酶(CDK)抑制剂,靶向CDK4(cyclin D1)和CDK6(cyclin D3)细胞周期途径,具有潜在的抗肿瘤活性。
In vitro | DMSO | 6 mg/mL (11.84 mM) | |
Water | Insoluble | ||
Ethanol | 8 mg/mL (15.79 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 19.74 mL | 98.7 mL | 197.4 mL |
0.5 mM | 3.95 mL | 19.74 mL | 39.48 mL |
1 mM | 1.97 mL | 9.87 mL | 19.74 mL |
5 mM | 0.39 mL | 1.97 mL | 3.95 mL |
*The above data is based on the productmolecular weight 506.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A12989 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 506.59 |
Formula | C27H32F2N8 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1231929-97-7 |
Synonyms | LY 2835219, LY-2835219 |
SMILES | CCN1CCN(CC1)CC2=CN=C(C=C2)NC3=NC=C(C(=N3)C4=CC5=C(C(=C4)F)N=C(N5C(C)C)C)F |
产品资料
产品标签
Product Questions
Product Questions
No Questions
您还可能对下列产品感兴趣
PHA-793887
PHA-793887是一种新型有效的CDK2,CDK5和CDK7抑制剂,IC50分别为8 nM,5 nM 和10 nM,作用于CDK2,5,和7比作用于CDK1…
BAY 1000394 (Roniciclib)
BAY 1000394 (Roniciclib)是一种口服生物利用细胞周期蛋白依赖性激酶(CDK)抑制剂,具有潜在的抗肿瘤活性。
BMS-265246
BMS-265246是cdk2/cyclin E和cdk1/cyclin B以及cdk4/cyclin D的强新吡唑并吡啶抑制剂。
Keywords:购买 LY2835219 (abemaciclib) | LY2835219 (abemaciclib) 供应商 | 订购 LY2835219 (abemaciclib) | LY2835219 (abemaciclib) 价格 | LY2835219 (abemaciclib) 生产商 | 订单 LY2835219 (abemaciclib) | LY2835219 (abemaciclib) 代理商 | 购买 1231929-97-7| 1231929-97-7 供应商 | 订购 1231929-97-7 | 1231929-97-7 价格 | 1231929-97-7 生产商 | 订单 1231929-97-7 | 1231929-97-7 代理商|buy LY2835219 (abemaciclib) | LY2835219 (abemaciclib) Supplier | purchase LY2835219 (abemaciclib) | LY2835219 (abemaciclib) cost | LY2835219 (abemaciclib) manufacturer | order LY2835219 (abemaciclib) | LY2835219 (abemaciclib) distributor | buy 1231929-97-7| 1231929-97-7 Supplier | purchase 1231929-97-7 | 1231929-97-7 cost | 1231929-97-7 manufacturer | order 1231929-97-7 | 1231929-97-7 distributor