产品详情
Medetomidine Hydrochloride是一种肾上腺素α2-受体激动剂,Ki为1.08 nM,比作用于α1-adrenoceptor选择性高1620倍。由于其镇痛和镇静作用而被用于兽医学。
靶点信息
α2-adrenoceptor | ||||
1.08 nM(Ki) |
In vitro (25°C) | DMSO | 12 mg/mL (50.68 mM) | |
Water | 45 mg/mL (190.08 mM) | ||
Ethanol | 45 mg/mL (190.08 mM) | ||
In vivo | Saline | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 42.24 mL | 211.2 mL | 422.4 mL |
0.5 mM | 8.45 mL | 42.24 mL | 84.48 mL |
1 mM | 4.22 mL | 21.12 mL | 42.24 mL |
5 mM | 0.84 mL | 4.22 mL | 8.45 mL |
*The above data is based on the productmolecular weight 236.74. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A13775 |
---|---|
作用机制 | Agonist (激动剂) |
M. Wt | 236.74 |
Formula | C13H16N2.HCl |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 86347-15-1 |
Synonyms | MonoHydrochloride, Domitor, MPV 785, Metomidine, Zalopine, Detomidine HCl |
SMILES | CC1=C(C(=CC=C1)C(C)C2=CN=CN2)C.Cl |
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