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￥ 0.00 Metabotropic glutamate receptors (mGluR)
50 个项目
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VU 0364770
Catalog No. A12139 mGlu4 receptors modulatorVU 0364770是mGlu4受体的正变构调节剂，在表达mGlu4的HEK 293细胞中EC50值为290 nM。 了解更多 -
(S)-3,5-DHPG
Catalog No. A16108 mGluR 激动剂(S)-3,5-DHPG是I类代谢型谷氨酸受体（mGluRs）的激动剂，与mGluR1a和mGluR5a（分别为Ki = 0.9和3.9 uM）结合，但不与离子型谷氨酸受体结合。 了解更多 -
Kainic acid monohydrate
Catalog No. A13485 Kainate receptor 激动剂Kainic acid monohydrate是海藻酸酯类离子型谷氨酸受体激动剂。可在体内诱发癫痫发作和神经退行性变，也已用于在啮齿动物中诱发实验性癫痫和检查兴奋性诱发的神经元凋亡机制。 了解更多 -
Ibotenic Acid
Catalog No. A14006 NMDA& mGlu receptor 激动剂Ibotenic Acid是最初从鹅膏菌属物种中分离出来的一种神经兴奋性氨基酸，它起着NMDA和代谢型谷氨酸受体激动剂的作用。 了解更多 -
A-841720
Catalog No. A13854 -
ADX-47273
Catalog No. A11181 -
LY2140023 (LY404039)
Catalog No. A10544 mGluR 激动剂LY-404039是一种用于科学研究的药物，用作代谢型谷氨酸受体II亚型mGluR2和mGluR3的选择性激动剂。它在动物研究中具有抗焦虑和抗精神病作用，但不会引起镇静作用。早期的人体试验使用LY-404，039前药形式LY-214，0023，也取得了令人鼓舞的结果。 了解更多 -
VU 0357121
Catalog No. A11754 -
VU 0364439
Catalog No. A12664 -
SIB 1757
Catalog No. A13758 -
VU 0361737
Catalog No. A12467 mGlu4 receptors modulatorVU 0361737是mGluR-4的选择性正变构调节剂（人和大鼠受体的EC50值分别为240和110 nM）。 了解更多 -
Mavoglurant
Catalog No. A21223 mGlu5 receptor antagonistMavoglurant is a structurally novel, non-competitive mGlu5 receptor antagonist, has an IC50 of 30 nM in a functional assay with human mGluR5. 了解更多 -
Basimglurant
Catalog No. A21225 mGlu5 negative allosteric modulatorBasimglurant (RG7090) is a potent, selective and orally available mGlu5 negative allosteric modulator with a Kd of 1.1 nM. 了解更多 -
Mavoglurant racemate
Catalog No. A21799 mGlu5 receptor antagonistMavoglurant (racemate) is the racemate of mavoglurant. Mavoglurant is a novel, non-competitive mGlu5 receptor antagonist. 了解更多 -
(R)-ADX-47273
Catalog No. A21887 mGluR5 positive allosteric modulator(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator, with an EC50 of 168 nM for potentiation . 了解更多 -
Methoxy-PEPy
Catalog No. A21899 mGlu5 receptor antagonistMethoxy-PEPy is a potent and highly selective mGlu5 receptor antagonist with IC50 of 1 nM. 了解更多 -
(1R,2S)-VU0155041
Catalog No. A21933 partial mGluR4 agonist(1R,2S)-VU0155041, Cis regioisomer of VU0155041, is a partial mGluR4 agonist with an EC50 of 2.35 μM. 了解更多 -
CHPG sodium salt
Catalog No. A21968 mGluR5 agonistCHPG sodium salt is a selective mGluR5 agonist, and attenuates SO2-induced oxidative stress and inflammation through TSG-6/NF-κB pathway in BV2 microglial cells. 了解更多 -
O-Phospho-L-serine
Catalog No. A21159 group III mGluR receptors agonistO-Phospho-L-serine is the immediate precursor to L-serine in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2. 了解更多 -
Dipraglurant
Catalog No. A11382 mGluR5 antagonistsDipraglurant (ADX 48621) is a mGluR5 antagonists with IC50 of 0.021 μM. 了解更多 -
Lu AF21934
Catalog No. A12140 mGlu4 receptor modulatorLu AF21934 is a selective and brain-penetrant mGlu4 receptor positive allosteric modulator with an IC50 of 500 nM for human mGlu4. 了解更多 -
BMT-145027
Catalog No. A12457 mGluR5 positive allosteric modulatorBMT-145027 is an mGluR5 positive allosteric modulator without inherent agonist activity, exhibits an EC50 of 47 nM. 了解更多 -
CBiPES HCl
Catalog No. A15811 -
MTEP hydrochloride
Catalog No. A15174
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- Inhibitor (抑制剂) (1)
- Agonist (激动剂) (14)
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- Modulator (调节剂) (15)
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