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MI-773 (SAR405838)是一种新的MDM2-p53相互作用的小分子抑制剂，以高亲和力（Ki = 0.88 nM）结合MDM2，并阻断p53-MDM2相互作用。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.78 mL | 88.89 mL | 177.78 mL |
| 0.5 mM | 3.56 mL | 17.78 mL | 35.56 mL |
| 1 mM | 1.78 mL | 8.89 mL | 17.78 mL |
| 5 mM | 0.36 mL | 1.78 mL | 3.56 mL |
*The above data is based on the productmolecular weight 562.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A14423 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 562.5 |
| Formula | C29H34Cl2FN3O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1303607-07-9 |
| Synonyms | MI 773, MI773 |
| SMILES | CC(C)(C)C[C@@H]1[C@]2([C@H]([C@@H](N1)C(=O)NC3CCC(CC3)O)C4=C(C(=CC=C4)Cl)F)C5=C(C=C(C=C5)Cl)NC2=O |
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