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Mibefradil dihydrochloride是钙通道阻滞剂，对T型Ca2+通道具有中等选择性，对T型和L型通道的IC50值分别为2.7 uM和18.6 uM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.59 mL | 87.94 mL | 175.89 mL |
| 0.5 mM | 3.52 mL | 17.59 mL | 35.18 mL |
| 1 mM | 1.76 mL | 8.79 mL | 17.59 mL |
| 5 mM | 0.35 mL | 1.76 mL | 3.52 mL |
*The above data is based on the productmolecular weight 568.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12482 |
|---|---|
| 作用机制 | Blocker (阻断剂) |
| M. Wt | 568.55 |
| Formula | C29H40Cl2FN3O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 116666-63-8 |
| Synonyms | Ro 40-5967 |
| SMILES | CC(C)C1C2=C(CCC1(CCN(C)CCCC3=NC4=CC=CC=C4N3)OC(=O)COC)C=C(C=C2)F.Cl.Cl |
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