你的浏览器似乎禁用了 JavaScript。
您必须在浏览器中启用JavaScript才能使用本网站的功能。

微信关注
申请试用装

主页 /
Microbiology

Microbiology

Quick View
Clindamycin Phosphate

Catalog No. A16460
Quick View

添加到收藏
Clindamycin Phosphate是用于恶性疟原虫的林可酰胺抗生素，IC50为12 nM。了解更多

Bulk Inquiry
Quick View
Clioquinol

Catalog No. A16461
Quick View

添加到收藏
Clioquinol是一种口服可生物利用的，亲脂性的，结合铜的卤代8-羟基喹啉，具有抗真菌，抗寄生虫和潜在的抗肿瘤活性。了解更多

Bulk Inquiry
Quick View
Clopidol

Catalog No. A16464
Quick View

添加到收藏
Clopidol是一种有机化合物，在兽药中用作抗球虫药。了解更多

Bulk Inquiry
Quick View
Closantel

Catalog No. A16466
Quick View

添加到收藏
Closantel是革兰氏阳性抗菌活性抑制剂，可抑制KinA/Spo0F系统，IC50为3.8μM。了解更多

Bulk Inquiry
Quick View
Closantel Sodium

Catalog No. A16467
Quick View

添加到收藏
Closantel Sodium是革兰氏阳性抗菌活性抑制剂，可抑制KinA/Spo0F系统，IC50为3.8μM。了解更多

Bulk Inquiry
Quick View
Cloxiquine

Catalog No. A16468
Quick View

添加到收藏
Cloxiquine是一种抗菌，抗真菌，抗衰老和抗结核药。了解更多

Bulk Inquiry
Quick View
Colistin Sulfate

Catalog No. A16469
Quick View

添加到收藏
Colistin Sulfate是连接到脂肪酸侧链的环状阳离子十肽，它属于一组结构相似的细菌抗菌肽。了解更多

Bulk Inquiry
Quick View
Cyromazine

Catalog No. A16473
Quick View

添加到收藏
Cyromazine是一种三嗪昆虫生长调节剂，用作杀虫剂和杀螨剂。了解更多

Bulk Inquiry
Quick View
BX471

Catalog No. A14409
Quick View

添加到收藏
CCR1 拮抗剂

BX471是一种有效的选择性非肽CCR1拮抗剂（对于人CCR1，Ki = 1 nM），对CCR1的选择性是CCR2，CCR5和CXCR4的250倍。了解更多

Bulk Inquiry
Quick View
TAK-779

Catalog No. A13846
Quick View

添加到收藏
CCR5 拮抗剂

TAK-779是一种新颖，有效和选择性的CCR5小分子拮抗剂，在结合试验中IC50值为1.4nM。了解更多

Bulk Inquiry
Quick View
Cenicriviroc

Catalog No. A13643
Quick View

添加到收藏
CCR2/CCR5 抑制剂

Cenicriviroc是用于治疗HIV感染的实验性候选药物.Cenicriviroc是CCR2和CCR5受体的抑制剂，可使其充当阻止病毒进入人体细胞的进入抑制剂。了解更多

Bulk Inquiry
Quick View
Aplaviroc

Catalog No. A13471
Quick View

添加到收藏
CCR5 entry 抑制剂

Aplaviroc是一种CCR5进入抑制剂，用于治疗HIV感染。了解更多

Bulk Inquiry
Quick View
BMS-813160

Catalog No. A17040
Quick View

添加到收藏
CCR2/CCR5 拮抗剂

BMS-813160是一种有效的选择性CCR2/CCR5拮抗剂，具有潜在的免疫调节和抗肿瘤活性。了解更多

Bulk Inquiry
Quick View
Cenicriviroc Mesylate

Catalog No. A17028
Quick View

添加到收藏
CCR2/5 receptors 抑制剂

Cenicriviroc(TAK-652,TBR-652)是CCR2和CCR5受体的抑制剂，可使其充当防止病毒进入人细胞的进入抑制剂了解更多

Bulk Inquiry
Quick View
BI-639667

Catalog No. A18747
Quick View

添加到收藏
Human CCR1 拮抗剂

BI-639667 is a potent and selective antagonist of human CCR1. 了解更多

Bulk Inquiry
Quick View
PF-04634817

Catalog No. A18659
Quick View

添加到收藏
CCR2 /CCR5 dual 拮抗剂

PF-04634817 is an orally administered CCR2 and CCR5 chemokine receptor antagonist, for the treatment of diabetic nephropathies and diabetic macular oedema. 了解更多

Bulk Inquiry
Quick View
LMD-009

Catalog No. A18643
Quick View

添加到收藏
CCR8 激动剂

LMD-009 is a selective CCR8 nonpeptide agonist. LMD-009 mediates chemotaxis, inositol phosphate accumulation, and calcium release in high potencies with EC50s from 11 to 87 nM. 了解更多

Bulk Inquiry
Quick View
INCB3344

Catalog No. A11465
Quick View

添加到收藏
CCR2 拮抗剂

INCB3344 is a potent, selective and orally bioavailable CCR2 antagonist with IC50 values of 5.1 nM (hCCR2) and 9.5 nM (mCCR2) in binding antagonism and 3.8 nM (hCCR2) and 7.8 nM (mCCR2) in antagonism of chemotaxis activity. 了解更多

Bulk Inquiry
Quick View
GW 766994

Catalog No. A20039
Quick View

添加到收藏
CCR3 拮抗剂

GW 766994 is a specific and oral chemokine receptor-3 (CCR3) antagonist, which has entered clinical trial for asthma and eosinophilic bronchitis. 了解更多

Bulk Inquiry
Quick View
AZ084

Catalog No. A19143
Quick View

添加到收藏
CCR8 拮抗剂

AZ084 is a potent, selective, allosteric and oral active CCR8 antagonist, with a Ki of 0.9 nM. Has potential to treat asthma. 了解更多

Bulk Inquiry
Quick View
ML604086

Catalog No. A18969
Quick View

添加到收藏
CCR8 抑制剂

ML604086 is a selective CCR8 inhibitor, inhibiting CCL1 binding to CCR8 on circulating T-cells. ML604086 inhibits CCL1 mediated chemotaxis and increases in intracellular Ca2+ concentrations. 了解更多

Bulk Inquiry
Quick View
CCR4 antagonist 2

Catalog No. A18471
Quick View

添加到收藏
CCR4 拮抗剂

CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits Treg trafficking into the Tumor Microenvironment without suppressing the number of Treg in healthy tissues. 了解更多

Bulk Inquiry
Quick View
Maraviroc (UK-427857)

Catalog No. A10556
Quick View

添加到收藏
CCR 拮抗剂

Maraviroc (UK-427857)是CCR5受体拮抗剂类别的抗逆转录病毒药物，用于治疗HIV感染。了解更多

Product Citations (3)

Bulk Inquiry Free Sample
- Roman V Uzhachenko, .et al. Metabolic modulation by CDK4/6 inhibitor promotes chemokine-mediated recruitment of T cells into mammary tumors, Cell Rep, 2021, Apr 6;35(1):108944 PMID: 33826903
- Karampoor S, .et al. Maraviroc attenuates the pathogenesis of experimental autoimmune encephalitis, Int Immunopharmacol, 2020, Mar;80:106138 PMID: 32007705
- Taisuke Ito, .et al. CCR5 is a novel target for the treatment of experimental alopecia areata, JCIA, 2020, 22 January
Quick View
Vicriviroc Malate

Catalog No. A10971
Quick View

添加到收藏
CCR5 拮抗剂

Vicriviroc Malate是CCR5拮抗剂，也是HIV-1进入靶细胞的有效抑制剂，对HIV分离株的平均IC50 = 0.46 nM，IC50 = 1?10 nM（n = 52）。了解更多

Product Citations (1)

Bulk Inquiry Free Sample
- Tomohiro Nabekura, .et al. Effects of Antiviral Drugs on Organic Anion Transport in Human Placental BeWo Cells, Antimicrob Agents Chemother, 2015, Dec; 59(12): 7666-7670 PMID: 26416870
Quick View
INCB8761 (PF-4136309)

Catalog No. A11136
Quick View

添加到收藏
CCR2 拮抗剂

INCB8761 (PF-4136309)是一种有效的，选择性的，口服可生物利用的CCR2拮抗剂。了解更多

Bulk Inquiry
Quick View
INCB 3284 dimesylate

Catalog No. A11104
Quick View

添加到收藏
HCCR2 拮抗剂

INCB 3284 dimesylate是一种有效的选择性hCCR2拮抗剂，对单核细胞趋化因子分子与hCCR2的结合和趋化活性表现出强烈的拮抗作用。了解更多

Bulk Inquiry Free Sample
Quick View
MK-0812

Catalog No. A11127
Quick View

添加到收藏
CCR2 拮抗剂

MK-0812是一种有效的选择性CCR2拮抗剂，对人单核细胞上CCR2的亲和力低，而在趋化性测定中的亲和力却低。它在临床前物种中具有良好的PK分布，并在动物模型中证明了功效。了解更多

Product Citations (1)

Bulk Inquiry
- Murakami K, .et al. CC chemokine ligand 2 and CXC chemokine ligand 8 as neutrophil chemoattractant factors in canine idiopathic polyarthritis, Vet Immunol Immunopathol, 2016, Dec;182:52-58 PMID: 27863550
Quick View
RS 504393

Catalog No. A15227
Quick View

添加到收藏
CCR2 拮抗剂

RS 504393是一种选择性CCR2趋化因子受体拮抗剂（IC50值分别为98 nM和> 100 uM，分别抑制人重组CCR2b和CCR1受体）。了解更多

Bulk Inquiry
Quick View
Vicriviroc maleate

Catalog No. A15276
Quick View

添加到收藏
CCR5 拮抗剂

Vicriviroc maleate是一种CCR5拮抗剂，在临床开发中用于治疗HIV-1的IC50为0.91 nM。了解更多

Bulk Inquiry
Quick View
NSC5844

Catalog No. A15924
Quick View

添加到收藏
CCR1 激动剂

NSC5844是具有C-C趋化因子受体1型（CCR1）激动特性的双喹啉化合物。了解更多

Bulk Inquiry
Quick View
ZK-756326 dihydrochloride

Catalog No. A16363
Quick View

添加到收藏
CCR8 激动剂

ZK-756326是有效的，选择性的非肽CCR8趋化因子受体激动剂。ZK 756326抑制了CCR8配体I-309（CCL1）的结合，IC（50）值为1.8μM。了解更多

Bulk Inquiry
Quick View
Bevirimat

Catalog No. A14194
Quick View

添加到收藏
HIV-1 maturation 抑制剂

Bevirimat (PA-457,MPC-4326,YK FH312) 是HIV-1病毒颗粒成熟抑制剂。了解更多

Product Citations (1)

Bulk Inquiry
- Mingzhang Wang, .et al. Quenching protein dynamics interferes with HIV capsid maturation, Nat Commun, 2017, 8: 1779 PMID: 29176596
Quick View
BMS-663068 (Fostemsavir)

Catalog No. A15025
Quick View

添加到收藏
HIV-1 attachment 抑制剂

BMS-663068 (Fostemsavir)是治疗HIV-1感染的HIV-1附着抑制剂。了解更多

Product Citations (1)

Bulk Inquiry
- Min Li, .et al. Clearance of HIV infection by selective elimination of host cells capable of producing HIV, Nat Commun, 2020, 11: 4051 PMID: 32792548
Quick View
BMS-663068 Tris

Catalog No. A15026
Quick View

添加到收藏
HIV-1 attachment 抑制剂

BMS-663068 tris是HIV-1附着抑制剂，可用于治疗HIV-1感染。了解更多

Bulk Inquiry
Quick View
Fosamprenavir Calcium Salt

Catalog No. A15089
Quick View

添加到收藏
HIV protease 抑制剂

Fosamprenavir Calcium Salt 是抗逆转录病毒蛋白酶抑制剂amprenavir的磷酸酯前药，与母体分子相比具有更高的溶解度，并有可能减轻当前给药方案中的药丸负担；GW433908G是前药的钙盐。了解更多

Bulk Inquiry
Quick View
Tipranavir

Catalog No. A15262
Quick View

添加到收藏
HIV protease 抑制剂

Tipranavir是一种非肽类HIV蛋白酶抑制剂（NPPI），可抑制HIV-1蛋白酶的酶促活性和二聚作用，对多种抗PI的HIV-1分离株具有有效的活性。了解更多

Bulk Inquiry
Quick View
Enfuvirtide Acetate(T-20)

Catalog No. A15825
Quick View

添加到收藏
HIV fusion 抑制剂

Enfuvirtide Acetate (T-20)是一个36个氨基酸的肽段，对应于gp41（HIV-1包膜蛋白的跨膜亚基）区域。了解更多

Bulk Inquiry
Quick View
Trovirdine

Catalog No. A13199
Quick View

添加到收藏
HIV-1 RT 抑制剂

Trovirdine当使用杂聚合引物/模板（寡DNA/核糖体RNA）和dGTP作为底物时，trovirdine抑制HIV-1 RT的IC50为7 nM。了解更多

Bulk Inquiry
Quick View
Nelfinavir

Catalog No. A11504
Quick View

添加到收藏
HIV-1 protease 抑制剂

Nelfinavir是一种有效的口服生物可利用的人类免疫缺陷病毒HIV-1蛋白酶抑制剂(Ki=2 nM ),广泛用于与HIV逆转录酶抑制剂联合治疗HIV感染。了解更多

Product Citations (2)

Bulk Inquiry
- Reiko Watanabe, .et al. Development of an In Silico Prediction Model for P-glycoprotein Efflux Potential in Brain Capillary Endothelial Cells toward the Prediction of Brain Penetration, J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967
- Yang PM, .et al. p38α/S1P/SREBP2 activation by the SAM-competitive EZH2 inhibitor GSK343 limits its anticancer activity but creates a druggable vulnerability in hepatocellular carcinoma, Am J Cancer Res, 2019, Oct 1;9(10):2120-2139 PMID: 31720078
Quick View
(±)-BI-D

Catalog No. A16024
Quick View

添加到收藏
Allosteric IN 抑制剂

(±)-BI-D 是有效的ALLINI（一种变构IN抑制剂），在LEDGF/p75结合位点结合整合酶。了解更多

Bulk Inquiry
Quick View
GSK2838232

Catalog No. A15965
Quick View

添加到收藏
HIV maturation 抑制剂

GSK2838232是一种新型的人类免疫病毒（HIV）成熟抑制剂，正在开发用于治疗慢性HIV感染。了解更多

Bulk Inquiry
Quick View
Darunavir

Catalog No. A20829
Quick View

添加到收藏
HIV protease inhibitor

Darunavir is an HIV protease inhibitor 了解更多

Bulk Inquiry
Quick View
Ritonavir

Catalog No. A10799
Quick View

添加到收藏
HIV Protease 抑制剂

Ritonavir是一种蛋白酶抑制剂，具有抗人类免疫缺陷病毒1型(hiv-1)的活性。蛋白酶抑制剂阻断hiv中被称为蛋白酶的部分，利托那韦抑制hiv病毒蛋白酶，这种蛋白酶防止gag-pol多蛋白的裂解，从而产生非感染性的未成熟病毒颗粒。了解更多

Bulk Inquiry Free Sample
Quick View
Lopinavir (ABT-378)

Catalog No. A10537
Quick View

添加到收藏
HIV Protease 抑制剂

Lopinavir (ABT-378)是HIV蛋白酶的抑制剂。了解更多

Bulk Inquiry Free Sample
Quick View
Atazanavir sulfate (BMS-232632-05)

Catalog No. A10096
Quick View

添加到收藏
HIV Protease 抑制剂

Atazanavir sulfate (BMS-232632-05)是蛋白酶抑制剂（PI）类的抗逆转录病毒药物。是一种高选择性的 HIV-1蛋白酶抑制剂。了解更多

Bulk Inquiry
Quick View
Atazanavir

Catalog No. A10097
Quick View

添加到收藏
HIV Protease 抑制剂

Atazanavir是一种氮杂肽及HIV-蛋白酶抑制剂，常与其他抗HIV药物结合，用于治疗HIV感染以及获得性免疫缺乏综合征。了解更多

Bulk Inquiry Free Sample
Quick View
Saquinavir

Catalog No. A11378
Quick View

添加到收藏
HIV Protease 抑制剂

Saquinavir是蛋白酶抑制剂。蛋白酶是将蛋白质分子切割成更小片段的酶。Saquinavir抑制HIV-1和HIV-2蛋白酶。了解更多

Product Citations (1)

Bulk Inquiry
- Reiko Watanabe, .et al. Development of an In Silico Prediction Model for P-glycoprotein Efflux Potential in Brain Capillary Endothelial Cells toward the Prediction of Brain Penetration, J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967
Quick View
Amprenavir

Catalog No. A11985
Quick View

添加到收藏
Amprenavir是一种人类免疫缺陷病毒（HIV）蛋白酶抑制剂，对于野生型HIV分离株，IC50为14.6±12.5 ng/ml。了解更多

Product Citations (1)

Bulk Inquiry Free Sample
- Reiko Watanabe, .et al. Development of an In Silico Prediction Model for P-glycoprotein Efflux Potential in Brain Capillary Endothelial Cells toward the Prediction of Brain Penetration, J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967
Quick View
Indinavir sulfate

Catalog No. A11871
Quick View

添加到收藏
Indinavir sulfate是HIV-1蛋白酶抑制剂。了解更多

Bulk Inquiry
Quick View
Darunavir Ethanolate (Prezista)

Catalog No. A11853
Quick View

添加到收藏
HIV protease 抑制剂

Darunavir Ethanolate (Prezista)是一种HIV蛋白酶抑制剂。了解更多

Bulk Inquiry Free Sample

联系我们

Not your Region? View all Distributors

溶液配制计算器

分子量计算器

稀释计算器

摩尔浓度计算器

ADOOQ 产品质量保证

Guaranteed product quality, 365 days Unconditional Return & Replacement

We promise all products to perform as described.