你的浏览器似乎禁用了 JavaScript。
您必须在浏览器中启用JavaScript才能使用本网站的功能。

微信关注
申请试用装

主页 /
Cytoskeleton /
Microtubules

Microtubules

Quick View
CK-636

Catalog No. A13827
Quick View

添加到收藏
Arp2/3 抑制剂

CK-636是一种Arp2/3复合抑制剂。CK-636在Arp2和Arp3之间结合，似乎阻止了Arp2和Arp3进入其活性构象。了解更多

Bulk Inquiry
Quick View
Cabazitaxel

Catalog No. A11831
Quick View

添加到收藏
Microtubule Associated 抑制剂

Cabazitaxel是一种天然紫杉烷的半合成衍生物。Cabazitaxel联合泼尼松是基于多西他赛的激素难治性前列腺癌的治疗选择。了解更多

Product Citations (2)

Bulk Inquiry Free Sample
- Satoshi Endo, .et al. Targeting Nrf2-antioxidant signaling reverses acquired cabazitaxel resistance in prostate cancer cells, J Biochem, 2021, Mar 17 PMID: 33729485
- Tomohiro Nabekura, .et al. Microtubule-targeting anticancer drug eribulin induces drug efflux transporter P-glycoprotein, Biochem Biophys Rep, 2020, Mar; 21: 100727 PMID: 31993509
Quick View
CW069

Catalog No. A13735
Quick View

添加到收藏
Microtubule Associated 抑制剂

CW069是微管运动蛋白HSET的变构和选择性抑制剂，IC50为75 uM，相对于KSP具有明显的选择性。了解更多

Bulk Inquiry
Quick View
INH1

Catalog No. A13872
Quick View

添加到收藏
Hec1 imhibitor

INH1是Hec1抑制剂。它结合Hec1，抑制其与Nek2和动植物的联系。了解更多

Bulk Inquiry
Quick View
INH6

Catalog No. A14200
Quick View

添加到收藏
Hec1 抑制剂

INH6是一种有效的Hec1抑制剂，可特异性破坏Hec1/Nek2相互作用并引起染色体错位。了解更多

Bulk Inquiry
Quick View
Cucurbitacin B

Catalog No. A14665
Quick View

添加到收藏
Microtubule polymerization 抑制剂

Cucurbitacin B是一种天然的三萜类化合物，以其强大的抗癌活性而闻名，研究表明该化合物抑制JAK/STAT3途径。也是一种有效的微管聚合抑制剂。了解更多

Bulk Inquiry Free Sample
Quick View
Mc-MMAD

Catalog No. A15156
Quick View

添加到收藏
Tubulin 抑制剂

Mc-MMAD有效的微管蛋白抑制剂，Monomethyl auristatin D (MMAD)是抗体药物偶联物中的毒素有效载荷；Mc-MMAD是保护基（马来酰亚胺基己酰基）偶联的MMAD。了解更多

Bulk Inquiry
Quick View
MMAD

Catalog No. A15172
Quick View

添加到收藏
Tubulin 抑制剂

MMAD是一种有效的微管蛋白抑制剂，是抗体药物偶联物中的毒素有效负载。了解更多

Bulk Inquiry
Quick View
Vc-MMAD

Catalog No. A15273
Quick View

添加到收藏
Tubulin 抑制剂

Vc-MMAD由ADC接头（Val-Cit）和有效的微管蛋白抑制剂（MMAD）组成，Vc-MMAD是抗体药物偶联物。" 了解更多

Bulk Inquiry
Quick View
D-64131

Catalog No. A14442
Quick View

添加到收藏
Tubulin 抑制剂

D-64131是微管蛋白聚合的新型抑制剂，可在体外抑制肿瘤细胞增殖（IC50 = 74 nM）。了解更多

Bulk Inquiry
Quick View
Vinblastine sulfate

Catalog No. A13661
Quick View

添加到收藏
microtubule dynamics 抑制剂

Vinblastine sulfate在无细胞试验中抑制微管形成并抑制nAChR活性，IC50为8.9μM，用于治疗某些类型的癌症。了解更多

Bulk Inquiry
Quick View
DM1-Sme

Catalog No. A15960
Quick View

添加到收藏
maytansinoid microtubular 抑制剂

DM1-SMe是一种有效的美登木素生物碱微管抑制剂，是未结合的DM1，是与硫代甲烷混合的二硫化物，用于封端巯基。了解更多

Bulk Inquiry
Quick View
TRx0237 (LMTX) mesylate

Catalog No. A16124
Quick View

添加到收藏
tau protein aggregation 抑制剂

TRx0237 (LMTX) mesylate是第二代tau蛋白聚集抑制剂，可用于治疗阿尔茨海默氏病（AD）和额颞痴呆。了解更多

Bulk Inquiry
Quick View
Tasidotin hydrochloride

Catalog No. A21944
Quick View

添加到收藏
microtubule assembly and microtubule dynamics inhibitor

Tasidotin hydrochloride is a peptide analog of the antimitotic depsipeptide dolastatin 15, as an inhibitor of microtubule assembly and microtubule dynamics. 了解更多

Bulk Inquiry
Quick View
CK-869

Catalog No. A20970
Quick View

添加到收藏
Arp2/3 complex inhibitor

CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor, with an IC50 of 7 μM. 了解更多

Bulk Inquiry
Quick View
CK-666

Catalog No. A20973
Quick View

添加到收藏
Arp2/3 complex inhibitor

CK-666 is a cell-permeable inhibitor of actin-related protein Arp2/3 complex, and binds to Arp2/3 complex, stabilizes the inactive state of the complex, blocking movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) conformation. 了解更多

Bulk Inquiry
Quick View
Entasobulin

Catalog No. A21027
Quick View

添加到收藏
??-tubulin polymerization inhibitor

Entasobulin is a β-tubulin polymerization inhibitor with potential anticancer activity. 了解更多

Bulk Inquiry
Quick View
Docetaxel (Taxotere)

Catalog No. A10326
Quick View

添加到收藏
Microtubule Associated 抑制剂

Docetaxel (Taxotere)多西他赛一种taxol类似物，是一种microtubules解聚抑制剂，通过结合于稳定的微管发挥作用。了解更多

Bulk Inquiry Free Sample
Quick View
Paclitaxel (Taxol)

Catalog No. A10689
Quick View

添加到收藏
Microtubule Associated 抑制剂

Paclitaxel (Taxol)是一种有丝分裂抑制剂，可稳定微管，从而干扰细胞分裂过程中微管的正常分解，在人内皮细胞中IC50为0.1pM。了解更多

Product Citations (5)

Bulk Inquiry Free Sample
- Yu Pan, .et al. The nature of the modification at position 37 of tRNAPhe correlates with acquired taxol resistance, Nucleic Acids Res, 2021, Jan 11;49(1):38-52 PMID: 33290562
- Li-Li Li, .et al. Resonance energy transfer sensitises and monitors in situ switching of LOV2-based optogenetic actuators, Nat Commun, 2020, Oct 9;11(1):5107 PMID: 33037199
- Baglo Y, .et al. Harnessing the Potential Synergistic Interplay Between Photosensitizer Dark Toxicity and Chemotherapy, Photochem Photobiol, 2019, Dec 19 PMID: 31856423
- Owiti AO, .et al. PSMA Antibody-Conjugated Pentablock Copolymer Nanomicellar Formulation for Targeted Delivery to Prostate Cancer, AAPS PharmSciTech, 2018, Nov;19(8):3534-3549 PMID: 30151731
- Owiti AO, .et al. Strategic Pentablock Copolymer Nanomicellar Formulation for Paclitaxel Delivery System, AAPS PharmSciTech, 2018, Oct;19(7):3110-3122 PMID: 30112614
Quick View
Vincristine sulfate

Catalog No. A10973
Quick View

添加到收藏
Tubulin 抑制剂

Vincristine sulfate是一种有丝分裂抑制剂。了解更多

Bulk Inquiry
Quick View
Epothilone A

Catalog No. A10359
Quick View

添加到收藏
Microtubule Associated 抑制剂

Epothilone A 通过稳定紫杉醇结合位点处的微管形成而起作用，并导致细胞周期停滞在G2/M转变，从而导致细胞毒性。了解更多

Bulk Inquiry
Quick View
Epothilone B (EPO906)

Catalog No. A10360
Quick View

添加到收藏
Microtubule Associated 抑制剂

Epothilone B (EPO906)是一种紫杉醇样microtubule稳定剂。了解更多

Product Citations (1)

Bulk Inquiry Free Sample
- Yicheng Zhu, .et al. Combinatrial treatment of anti-High Mobility Group Box-1 monoclonal antibody and epothilone B improves functional recovery after spinal cord contusion injury, Neurosci Res, 2021, Apr 17 PMID: 33864880
Quick View
Vinflunine Tartrate

Catalog No. A10975
Quick View

添加到收藏
Microtubule Associated 抑制剂

Vinflunine Tartrate是长春氟宁的酒石酸盐，它使微管不稳定，IC50为18.8 nM，并在细胞分裂过程中干扰微管的动力学。了解更多

Bulk Inquiry
Quick View
CYT997 (Lexibulin)

Catalog No. A10264
Quick View

添加到收藏
Microtubule 抑制剂

CYT997 (Lexibulin)是一种新型的抗癌血管分裂剂(VDA)。在体外，CYT997被证明可有效抑制血管内皮生长因子刺激的人脐静脉内皮细胞（IC（50）3.7±1.8 nM）的增殖，并在100 nM时引起明显的形态变化，包括膜起泡。了解更多

Bulk Inquiry Free Sample
Quick View
ABT-751 (E-7010)

Catalog No. A10024
Quick View

添加到收藏
Microtubule Associated 抑制剂

ABT-751 (E-7010)是一种抗有丝分裂剂，可抑制微管聚合，并在秋水仙碱位点与β-微管蛋白结合。在G2M期阻断细胞周期并诱导凋亡。了解更多

Bulk Inquiry Free Sample
Quick View
Ixabepilone

Catalog No. A11449
Quick View

添加到收藏
microtubule 抑制剂

Ixabepilone是epothilone B类似物。了解更多

Product Citations (3)

Bulk Inquiry Free Sample
- Dong-Sheng Cao, .et al. A Multi-Scale Systems Pharmacology Approach Uncovers the Anti-Cancer Molecular Mechanism of Ixabepilone, Eur J Med Chem, 2020, Aug 1;199:112421 PMID: 32428794
- Hoque M, .et al. Changes in cell morphology guide identification of tubulin as the off-target for protein kinase inhibitors, Pharmacol Res, 2018, Aug;134:166-178 PMID: 29944980
- APRIL L. RISINGER, .et al. Breast Cancer Cell Lines Exhibit Differential Sensitivities to Microtubule-targeting Drugs Independent of Doubling Time, Anticancer Res, 2015, Nov; 35(11): 5845-5850. PMID: 26504006
Quick View
Nocodazole

Catalog No. A13219
Quick View

添加到收藏
microtubule 抑制剂

Nocodazole是微管抑制剂；抑制有丝分裂。也抑制自噬体-溶酶体融合。了解更多

Bulk Inquiry Free Sample
Quick View
4-Demethylepipodophyllotoxin

Catalog No. A10014
Quick View

添加到收藏
microtubule assembly 抑制剂

4-Demethylepipodophyllotoxin是微管组装的有效抑制剂。了解更多

Bulk Inquiry

联系我们

Not your Region? View all Distributors

溶液配制计算器

分子量计算器

稀释计算器

摩尔浓度计算器

ADOOQ 产品质量保证

Guaranteed product quality, 365 days Unconditional Return & Replacement

We promise all products to perform as described.