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Mifepristone (Mifeprex)是一种抗氧化剂和糖皮质激素受体拮抗剂，具有抑制NFκB活化的能力，NFκB是一种影响各种粘附分子和几种炎症基因表达的核转录因子。
靶点信息
| Progesterone receptor | Glucocorticoid receptor | |||
| 0.2 nM | 2.6 nM |
| In vitro | DMSO | 77 mg/mL (179.24 mM) | |
| Water | Insoluble | ||
| Ethanol | 17 mg/mL (39.57 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.28 mL | 116.39 mL | 232.77 mL |
| 0.5 mM | 4.66 mL | 23.28 mL | 46.55 mL |
| 1 mM | 2.33 mL | 11.64 mL | 23.28 mL |
| 5 mM | 0.47 mL | 2.33 mL | 4.66 mL |
*The above data is based on the productmolecular weight 429.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10591 |
|---|---|
| M. Wt | 429.6 |
| Formula | C29H35NO2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 84371-65-3 |
| Synonyms | RU-486, Mifegyne |
| SMILES | CC#C[C@@]1(CC[C@@H]2[C@@]1(C[C@@H](C3=C4CCC(=O)C=C4CC[C@@H]23)C5=CC=C(C=C5)N(C)C)C)O |
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