Miltefosine

Name: Miltefosine
SKU: A14138

目录号: A14138

PI3K/Akt 抑制剂

Miltefosine Chemical Structure

CAS NO. 58066-85-6

Miltefosine在癌细胞系A431和HeLa中抑制PI3K/Akt活性，ED50为17.2μM和8.1μM。

库存：现货

规格	价格	数量
100 mg	￥ 455.00
500 mg	￥ 840.00
10mM * 1mL in DMSO	￥ 448.00

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生物活性

Miltefosine在癌细胞系A431和HeLa中抑制PI3K/Akt活性，ED50为17.2μM和8.1μM。

靶点信息

Akt	PI3K	PKC
N/A		~7 μM

溶解度 *

In vitro (25°C)	DMSO	Insoluble
	Water	77 mg/mL (188.92 mM)
	Ethanol	77 mg/mL (188.92 mM)
In vivo	Saline	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.53 mL	122.67 mL	245.34 mL
0.5 mM	4.91 mL	24.53 mL	49.07 mL
1 mM	2.45 mL	12.27 mL	24.53 mL
5 mM	0.49 mL	2.45 mL	4.91 mL

*The above data is based on the productmolecular weight 407.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A14138
作用机制	Inhibitor (抑制剂)
M. Wt	407.6
Formula	C21H46NO4P
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	58066-85-6
Synonyms	HePC
SMILES	CCCCCCCCCCCCCCCCOP(=O)([O-])OCC[N+](C)(C)C