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Miransertib hydrochloride (ARQ-092 hydrochloride) is a potent, orally active, selective and allosteric Akt inhibitor with IC50s of 2.7 nM, 14 nM and 8.1 nM for Akt1, Akt2, Akt3, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.32 mL | 106.61 mL | 213.23 mL |
| 0.5 mM | 4.26 mL | 21.32 mL | 42.65 mL |
| 1 mM | 2.13 mL | 10.66 mL | 21.32 mL |
| 5 mM | 0.43 mL | 2.13 mL | 4.26 mL |
*The above data is based on the productmolecular weight 468.98. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A22376 |
|---|---|
| M. Wt | 468.98 |
| Formula | C27H25ClN6 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 2 years |
| CAS No. | 1313883-00-9 |
| Synonyms | ARQ-092 hydrochloride, ARQ092, ARQ 092 |
| SMILES | NC1=NC=CC=C1C2=NC3=CC=C(C4=CC=CC=C4)N=C3N2C5=CC=C(C6(N)CCC6)C=C5.[H]Cl |
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