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MJN110是一种有效的MAGL选择性抑制剂,该酶主要负责降解内源性大麻素2-花生四烯酸甘油酯(2-AG),其选择性超过FAAH,FAAH是降解内源性大麻素大麻素(AEA)的水解酶。
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 21.63 mL | 108.15 mL | 216.3 mL |
0.5 mM | 4.33 mL | 21.63 mL | 43.26 mL |
1 mM | 2.16 mL | 10.81 mL | 21.63 mL |
5 mM | 0.43 mL | 2.16 mL | 4.33 mL |
*The above data is based on the productmolecular weight 462.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A16081 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 462.33 |
Formula | C22H21Cl2N3O4 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1438416-21-7 |
Synonyms | MJN-110, MJN 110 |
SMILES | C1CC(=O)N(C1=O)OC(=O)N2CCN(CC2)C(C3=CC=C(C=C3)Cl)C4=CC=C(C=C4)Cl |
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