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MK-0517 (Fosaprepitant,L-758,298)是Aprepitant的水溶性磷酰基前药，它是NK1拮抗剂。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.28 mL | 81.38 mL | 162.76 mL |
| 0.5 mM | 3.26 mL | 16.28 mL | 32.55 mL |
| 1 mM | 1.63 mL | 8.14 mL | 16.28 mL |
| 5 mM | 0.33 mL | 1.63 mL | 3.26 mL |
*The above data is based on the productmolecular weight 614.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11756 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 614.41 |
| Formula | C23H22F7N4O6P |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 172673-20-0 |
| Synonyms | MK-0517, L-758,298 |
| SMILES | C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O[C@@H]2[C@@H](N(CCO2)CC3=NC(=O)N(N3)P(=O)(O)O)C4=CC=C(C=C4)F |
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