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MK-0591 (Quiflapon)是一种选择性的特异性5-脂氧合酶激活蛋白（FLAP）抑制剂，在FLAP结合测定中的IC50值为1.6 nM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.03 mL | 85.15 mL | 170.31 mL |
| 0.5 mM | 3.41 mL | 17.03 mL | 34.06 mL |
| 1 mM | 1.7 mL | 8.52 mL | 17.03 mL |
| 5 mM | 0.34 mL | 1.7 mL | 3.41 mL |
*The above data is based on the productmolecular weight 587.17. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15163 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 587.17 |
| Formula | C34H35ClN2O3S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 136668-42-3 |
| Synonyms | Quiflapon, MK0591, MK 0591 |
| SMILES | CC(C)(C)SC1=C(N(C2=C1C=C(C=C2)OCC3=NC4=CC=CC=C4C=C3)CC5=CC=C(C=C5)Cl)CC(C)(C)C(=O)O |
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