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ML-314是神经降压素NTR1受体的脑渗透性非肽β-arrestin偏向性激动剂，在主要试验中对NTR1（EC50 = 2.0μM）表现出完全的激动剂行为，对NTR2具有选择性。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.8 mL | 118.99 mL | 237.97 mL |
| 0.5 mM | 4.76 mL | 23.8 mL | 47.59 mL |
| 1 mM | 2.38 mL | 11.9 mL | 23.8 mL |
| 5 mM | 0.48 mL | 2.38 mL | 4.76 mL |
*The above data is based on the productmolecular weight 420.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13570 |
|---|---|
| 作用机制 | Agonist (激动剂) |
| M. Wt | 420.22 |
| Formula | C24H28N4O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1448895-09-7 |
| Synonyms | ML 314, ML-314 |
| SMILES | COC1=CC=CC=C1N2CCN(CC2)C3=NC(=NC4=CC(=C(C=C43)OC)OC)C5CC5 |
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