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MLN1117，也称为INK1117和TAK-117，是具有潜在抗肿瘤活性的I类磷酸肌醇3激酶（PI3K）α同工型的生物利用抑制剂。
| In vitro | DMSO | 15 mg/mL (41.28 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.54 mL | 137.69 mL | 275.38 mL |
| 0.5 mM | 5.51 mL | 27.54 mL | 55.08 mL |
| 1 mM | 2.75 mL | 13.77 mL | 27.54 mL |
| 5 mM | 0.55 mL | 2.75 mL | 5.51 mL |
*The above data is based on the productmolecular weight 363.13. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15529 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 363.13 |
| Formula | C19H17N5O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1268454-23-4 |
| Synonyms | INK1117, INK-1117, INK 1117, MLN 1117, MLN-1117, TAK-117, TAK 117, TAK117 |
| SMILES | O=C(C1=CN=C2C=CC(C3=CC=C(OC(N)=N4)C4=C3)=CN21)N5CCOCC5 |
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