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MLT-747 is a potent, selective, allosteric inhibitor of MALT1, binds MALT1 in the allosteric Trp580 pocket, with an IC50 of 14 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.91 mL | 104.53 mL | 209.06 mL |
| 0.5 mM | 4.18 mL | 20.91 mL | 41.81 mL |
| 1 mM | 2.09 mL | 10.45 mL | 20.91 mL |
| 5 mM | 0.42 mL | 2.09 mL | 4.18 mL |
*The above data is based on the productmolecular weight 478.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A18942 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 478.33 |
| Formula | C20H21Cl2N7O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2097853-86-4 |
| Synonyms | MLT747, MLT 747 |
| SMILES | O=C(NC1=CC(Cl)=C(C(N2CCCC2)=O)N=C1)NC3=C([C@@H](OC)C)N4C(N=C3)=CC(Cl)=N4 |
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