Molidustat

Name: Molidustat
SKU: A14404

目录号: A14404

HIF-PH 抑制剂

Molidustat Chemical Structure

CAS NO. 1154028-82-6

Molidustat是一种新型的低氧诱导因子（HIF）脯氨酰羟化酶（PH）抑制剂，可刺激促红细胞生成素（EPO）的产生和红细胞的形成。

库存：现货

规格	价格	数量
5 mg	￥ 700.00
10 mg	￥ 1,050.00
25 mg	￥ 2,240.00

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生物活性

Molidustat是一种新型的低氧诱导因子（HIF）脯氨酰羟化酶（PH）抑制剂，可刺激促红细胞生成素（EPO）的产生和红细胞的形成。

靶点信息

PHD2	PHD3	PHD1
280 nM	450 nM	480 nM

溶解度 *

In vitro	DMSO	Warmed: 3 mg/mL (9.54 mM)
	Water	Insoluble
	Ethanol	DMF: 4 mg/mL (12.72 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	31.82 mL	159.08 mL	318.17 mL
0.5 mM	6.36 mL	31.82 mL	63.63 mL
1 mM	3.18 mL	15.91 mL	31.82 mL
5 mM	0.64 mL	3.18 mL	6.36 mL

*The above data is based on the productmolecular weight 314.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A14404
作用机制	Inhibitor (抑制剂)
M. Wt	314.3
Formula	C13H14N8O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1154028-82-6
Synonyms	BAY 85-3934, BAY85-3934, BAY853934
SMILES	C1COCCN1C2=NC=NC(=C2)N3C(=O)C(=CN3)N4C=CN=N4