MTX-211

Name: MTX-211
SKU: A18324

目录号: A18324

EGFR/PI3K 双重抑制剂

MTX-211 Chemical Structure

CAS NO. 1952236-05-3

MTX-211 is a dual inhibitor of EGFR and PI3K, which plays important roles in the progression of KRAS mutant colorectal cancer. MTX-211 has the potential for the treatment of KRAS mutant colorectal cancer.

库存：现货

规格	价格	数量
2 mg	￥ 840.00
5 mg	￥ 2,520.00
10 mg	￥ 3,850.00
50 mg	￥ 11,200.00

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生物活性

溶解度 *

In vitro	DMSO	22 mg/mL (45.99 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.91 mL	104.53 mL	209.06 mL
0.5 mM	4.18 mL	20.91 mL	41.81 mL
1 mM	2.09 mL	10.45 mL	20.91 mL
5 mM	0.42 mL	2.09 mL	4.18 mL

*The above data is based on the productmolecular weight 478.3234. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A18324
作用机制	Inhibitor (抑制剂)
M. Wt	478.3234
Formula	C20H14Cl2FN5O2S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1952236-05-3
Synonyms	MTX211, MTX 211
SMILES	CS(=O)(NC1=CC(C2=CC3=C(NC4=CC=C(F)C(Cl)=C4)N=CN=C3C=C2)=CN=C1Cl)=O