Mycophenolate mofetil (CellCept)

Name: Mycophenolate mofetil (CellCept)
SKU: A10613

目录号: A10613

IMPDH 抑制剂

Mycophenolate mofetil (CellCept) Chemical Structure

CAS NO. 128794-94-5

Mycophenolate mofetil (CellCept)是嘌呤生物合成（特别是鸟嘌呤合成）中肌苷单磷酸脱氢酶（IMPDH）的可逆抑制剂，对T细胞和B细胞的生长是必需的。

库存：现货

规格	价格	数量
50 mg	￥ 350.00
200 mg	￥ 700.00
500 mg	￥ 1,400.00
10mM * 1mL in DMSO	￥ 441.00

或

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生物活性

Mycophenolate mofetil (CellCept)是嘌呤生物合成（特别是鸟嘌呤合成）中肌苷单磷酸脱氢酶（IMPDH）的可逆抑制剂，对T细胞和B细胞的生长是必需的。

靶点信息

Inosine monophosphate dehydrogenase II	Inosine monophosphate dehydrogenase I
27 nM	39 nM

溶解度 *

In vitro (25°C)	DMSO	77 mg/mL (177.62 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	0.5% methylcellulose	19 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.07 mL	115.34 mL	230.68 mL
0.5 mM	4.61 mL	23.07 mL	46.14 mL
1 mM	2.31 mL	11.53 mL	23.07 mL
5 mM	0.46 mL	2.31 mL	4.61 mL

*The above data is based on the productmolecular weight 433.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10613
作用机制	Inhibitor (抑制剂)
M. Wt	433.5
Formula	C23H31NO7
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	128794-94-5
Synonyms	CellCept, RS 61443, TM-MMF
SMILES	CC1=C(C(=C(C2=C1COC2=O)O)C/C=C(\C)/CCC(=O)OCCN3CCOCC3)OC