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24 个项目
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Tebanicline hydrochloride
Catalog No. A21918 nAChR modulatorTebanicline hydrochloride (ABT594 hydrochloride) is a nAChR modulator with potent, orally effective analgesic activity. 了解更多 -
Varenicline Hydrochloride
Catalog No. A21539 α4β2 nAChR partial agonistVarenicline Hydrochloride (CP 526555 hydrochloride) is a high affinity, selective α4β2 nicotine acetylcholine receptor (nAChR) partial agonist and full α7 nAChR agonist. 了解更多 -
Bephenium hydroxynaphthoate
Catalog No. A17391 B-type AChR activatorBephenium hydroxynaphthoate is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis; B-type AChR activator. 了解更多 -
Tropisetron HCL
Catalog No. A14375 5-HT3 receptor 拮抗剂Tropisetron HCL是选择性的5-HT3受体拮抗剂和α7烟碱样受体激动剂，对5-HT3受体的IC50为70.1±0.9 nM。 了解更多 -
PNU-120596
Catalog No. A11203 -
Adiphenine HCl
Catalog No. A11716 -
Methyllycaconitine citrate
Catalog No. A12681 Methyllycaconitine citrate是含有α7的神经元烟碱受体（Ki = 1.4 nM）的有效拮抗剂。与浓度大于40 nM的α4β2和α6β2受体相互作用。 了解更多 -
PNU 282987
Catalog No. A11233 -
(-)-(S)-B-973B
Catalog No. A18761 α7 nAChR modulator-)-(S)-B-973B is a potent allosteric agonist and positive allosteric modulator of α7 nAChR, with antinociceptive activity. 了解更多 -
Mecamylamine Hydrochloride
Catalog No. A17884 nAChR antagonistMecamylamine hydrochloride is a nAChR antagonist previously used to treat hypertension. It displays a wide variety of activities, including reducing depression-like behaviors in subjects with Tourette's syndrome and improving rates of smoking cessation. 了解更多 -
Benzethonium Chloride
Catalog No. A13653 nAChR 抑制剂Benzethonium Chloride是nAChRs的有效抑制剂，可抑制α4β2nAChRs和α7nAChRs，IC50分别为49 nM和122 nM。 了解更多 -
GTS-21 (DMBX-A)
Catalog No. A15950 nAChR 激动剂GTS-21 dihydrochloride (DMBX-A)是一种选择性的α7烟碱乙酰胆碱受体激动剂，最近已被确定为一种有希望的炎症治疗方法。 了解更多 -
EVP-6124 hydrochloride
Catalog No. A15087 nAChR 抑制剂EVP-6124 hydrochloride是一种新型的α7神经元烟碱型乙酰胆碱受体（nAChRs）的部分激动剂。EVP-6124对α7nAChRs具有选择性，并且不激活或抑制异源α4β2nAChRs。 了解更多 -
EVP-6124 (Encenicline)
Catalog No. A15086 nAChR 抑制剂EVP-6124 (Encenicline)是α7神经元烟碱乙酰胆碱受体（nAChRs）的新型部分激动剂；显示对α7nAChRs的选择性，并且不激活或抑制异聚体α4β2nAChRs。 了解更多 -
A-582941
Catalog No. A13539 -
5-Iodo-A-85380 2HCl
Catalog No. A13639 -
Sofinicline (ABT-894, A-422894)
Catalog No. A13842 -
Ispronicline (TC-1734, AZD-3480)
Catalog No. A14183 nAChR 激动剂Ispronicline (TC-1734,AZD-3480)是神经元烟碱乙酰胆碱受体部分激动剂。Ispronicline是亚型选择性的，主要与a4b2亚型结合。它具有抗抑郁、益智和神经保护作用。 了解更多
24 个项目
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- Inhibitor (抑制剂) (4)
- Agonist (激动剂) (9)
- Antagonist (拮抗剂) (2)
- Activator (激活剂) (2)
- Modulator (调节剂) (6)
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