产品详情
Nebivolol hydrochloride是β1-肾上腺素受体的高度选择性拮抗剂(Ki = 0.88 nM,β2-肾上腺素受体Ki = 48 nM)。
靶点信息
β1-adrenoceptor | ||||
0.8 nM |
In vitro | DMSO | 81 mg/mL (183.3 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 22.63 mL | 113.15 mL | 226.3 mL |
0.5 mM | 4.53 mL | 22.63 mL | 45.26 mL |
1 mM | 2.26 mL | 11.31 mL | 22.63 mL |
5 mM | 0.45 mL | 2.26 mL | 4.53 mL |
*The above data is based on the productmolecular weight 441.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A10630 |
---|---|
M. Wt | 441.9 |
Formula | C22H25F2NO4.HCl |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 152520-56-4 |
Synonyms | R-67145 |
SMILES | C1CC2=C(C=CC(=C2)F)O[C@H]1[C@H](CNC[C@@H]([C@@H]3CCC4=C(O3)C=CC(=C4)F)O)O.Cl |
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