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￥ 0.00 Neuronal Signaling
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Etoricoxib
Catalog No. A13770 COX-2 抑制剂Etoricoxib特异性结合并抑制环氧合酶2（COX-2），从而抑制花生四烯酸向前列腺素的转化。抑制COX-2可以诱导细胞凋亡并抑制肿瘤细胞的增殖和血管生成。 了解更多 -
Xanthohumol
Catalog No. A15919 -
SC 560
Catalog No. A13023 -
Etodolac (AY-24236)
Catalog No. A10371 COX inhibitorEtodolac (AY-24236) is a non-steroidal anti-inflammatory compound that is a non-selective inhibitor of COX (IC50=53.5 nM). 了解更多 -
Eicosatetraynoic acid
Catalog No. A19008 COX/LOX inhibitorEicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygenase (ID50=8 μM and 4 μM, respectively). Eicosatetraynoic acid (ETYA) activates PPARα and PPARγ chimeras at 10 ?M?? 了解更多 -
Naproxen etemesil
Catalog No. A13052 COX-1 and COX-2 inhibitorNaproxen etemesil is a lipophilic, non-acidic, inactive prodrug of naproxen that is hydrolysed to pharmacologically active Naproxen once absorbed. Naproxen is a COX-1 and COX-2 inhibitor with IC50s of 8.72 and 5.15 μM, respectively in cell assay. 了解更多 -
Diclofenac diethylamine
Catalog No. A16503 COX inhibitorDiclofenac diethylamine is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor. 了解更多 -
Diclofenac
Catalog No. A17814 COX inhibitorDiclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 nM, 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1, 0.84 μM for ovine COX-1 and COX-2, respectively. 了解更多 -
Etoricoxib D4
Catalog No. A21877 COX-2 inhibitorEtoricoxib D4 (MK-0663 D4) is a deuterium labeled Etoricoxib. Etoricoxib is a non steroidal anti-inflammatory agent, acting as a selective and orally active COX-2 inhibitor, with IC50s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood. 了解更多 -
Jaceosidin
Catalog No. A12080 Jaceosidin是一种来源于艾蒿的药理活性黄酮，通过阻断培养的人乳腺上皮细胞中erk-1和-2的磷酸化来抑制佛波酯诱导的cox-2和MMP-9的上调。 了解更多 -
Amfenac Sodium Monohydrate
Catalog No. A16399 COX 抑制剂Amfenac Sodium Monohydrate是一种非甾体止痛消炎药，带有乙酸部分。COX1和COX2的IC50值分别为250 nM和150 nM。 了解更多 -
Carprofen
Catalog No. A16428 -
Timegadine
Catalog No. A17108 COX and lipo-oxygenase 抑制剂Timegadine被发现是一种有效的竞争性环加氧酶（COX）和脂加氧酶抑制剂，IC50的范围从5 nM（洗兔血小板）到20μM（大鼠脑）。在马血小板匀浆的细胞溶质级分和洗涤过的兔血小板中，脂氧化酶的浓度为100μM和100μM。 了解更多 -
Aceclofenac
Catalog No. A17433 COX-2 抑制剂Aceclofenac is a cyclooxygenase-2 inhibitor used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. 了解更多 -
Bromfenac sodium hydrate
Catalog No. A18194 COX-2 抑制剂Bromfenac Sodium Sesquihydrate is a nonsteroidal anti-inflammatory drug (NSAID), which inhibits cyclooxygenase II (COX-2). 了解更多 -
Metamizole sodium hydrate
Catalog No. A18270 COX 抑制剂Dipyrone, also known as Anador and NSC-73205, is a nonsteroidal anti-inflammatory drug used to treat pain (postoperative, colic, cancer, and migraine). 了解更多 -
Vigabatrin
Catalog No. A15277 GABA-transaminase 抑制剂Vigabatrin是抑制性神经递质β-氨基丁酸（GABA）的结构类似物，它不可逆地抑制GABA转氨酶对GABA的分解代谢。 了解更多 -
MRK-016
Catalog No. A12046 GABAA α5 receptor agonistMRK-016 is a selective, orally bioavailable inverse agonist of GABAA α5 receptor, with an EC50 of 3 nM for GABAA α5, and Kis of 0.83, 0.85, 0.77?and 1.4?nM for human?GABAA?α1β3γ2, GABAA?α2β3γ2, GABAA?α3β3γ2, and GABAA?α5β3γ2, respectively; MRK-016 also readily penetrates the CNS. 了解更多 -
Acamprosate calcium
Catalog No. A11308 GABA receptor agonistAcamprosate calcium(Campral EC) is a GABA receptor agonist and modulator of glutamatergic systems; reduces alcohol consumption in animal models of alcohol addiction. 了解更多 -
(R)-Baclofen
Catalog No. A16680 GABAB receptor agonist(R)-Baclofen(STX209) is a selective GABAB receptor agonist. 了解更多 -
Basmisanil
Catalog No. A21321 GABAAα5 modulatorBasmisanil is a highly selective GABAAα5 negative allosteric modulator. 了解更多 -
CP-409092 hydrochloride
Catalog No. A21397 GABAA receptor partial agonistCP-409092 hydrochloride is a partial agonist of GABAA receptor, with anti-anxiety activity. 了解更多 -
Gaboxadol hydrochloride
Catalog No. A21730 GABAA receptors agonistGaboxadol hydrochloride (Lu 02-030 hydrochloride) is a selective agonist at GABAA receptors that contain α4-δ subunits, and has anxiolytic and sedative effects. 了解更多 -
Dihydromyricetin (Ampeloptin)
Catalog No. A10252 -
Nefiracetam (Translon)
Catalog No. A10631 Nefiracetam (Translon)是认知增强剂。它激活L/N型钙通道，胆碱能，单胺能和GABA能系统。 了解更多 -
SKF 89976A HCl
Catalog No. A10849 GABA uptake 抑制剂SKF 89976A HCl是一种有效的GABA吸收抑制剂，hGAT-1，rGAT-2，hGAT-3和hBGT-1的IC50分别为0.13、550、944和7210μM。 了解更多 -
Flumazenil
Catalog No. A10397 Benzodiazepine 拮抗剂Flumazenil是竞争性抑制GABA/苯二氮卓受体复合物上苯二氮卓识别位点的活性。Flumazenil在一些活性动物模型中是弱部分激动剂，但在人类中很少或没有激动剂活性。 了解更多
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