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Radiprodil
Catalog No. A21193 NMDA NR2B antagonistRadiprodil (RGH-896) is an orally active and selective NMDA NR2B antagonist. A potential therapeutic agent in treatment of neuropathic pain and possibly other chronic pain conditions. 了解更多 -
7-Chlorokynurenic acid sodium salt
Catalog No. A21879 NMDA receptor antagonist7-Chlorokynurenic acid sodium salt is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 了解更多 -
SDZ 220-581 hydrochloride, SDZ220-581, SDZ-220-581
Catalog No. A21897 NMDA receptor antagonistSDZ 220-581 hydrochloride is an orally active, potent, competitive NMDA receptor antagonist with pKi value of 7.7. 了解更多 -
Rislenemdaz
Catalog No. A21907 NMDA receptor GluN2B antagonistRislenemdaz (CERC-301) is an orally bioavailable and selective N-methyl-D-aspartate (NMDA) receptor subunit 2B (GluN2B) antagonist with Ki and IC50 of 8.1 nM and 3.6 nM, respectively. 了解更多 -
Memantine hydrochloride
Catalog No. A11708 NMDA receptor 拮抗剂Memantine hydrochloride是nmda受体的拮抗剂，与离子通道位点结合。它还是CYP2B6和CYP2D6抑制剂，作用于重组CYP2B6和CYP2D6，Ki分别为0.51 nM和94.9 μM。它被用于治疗帕金森综合征。 了解更多 -
Orphenadrine citrate
Catalog No. A11712 -
NVP-AAM077 Tetrasodium Hydrate (PEAQX)
Catalog No. A14071 -
GLYX-13 (Rapastinel)
Catalog No. A13576 -
Ibotenic Acid
Catalog No. A14006 NMDA& mGlu receptor 激动剂Ibotenic Acid是最初从鹅膏菌属物种中分离出来的一种神经兴奋性氨基酸，它起着NMDA和代谢型谷氨酸受体激动剂的作用。 了解更多 -
CIQ
Catalog No. A15523 -
RO 25-6981 maleate
Catalog No. A16083 NMDA receptors blockerRO 25-6981 maleate是含有NR2B亚基的NMDA受体的强效和选择性活性依赖性阻断剂。克隆的受体亚基组合NR1C/NR2B和NR1C/NR2A的IC50值分别为0.009和52 uM。 了解更多 -
Ro 25-6981 maleate
Catalog No. A13144 -
D-AP5
Catalog No. A17044 -
Mephenesin
Catalog No. A17493 NMDA receptor antagonistMephenesin is an NMDA receptor antagonist, is a centrally acting muscle relaxant. 了解更多 -
CaMKII-IN-1
Catalog No. A21034 CaMKII inhibitorCaMKII-IN-1 is a potent and highly selective CaMKII inhibitor with IC50 of 63 nM. 了解更多 -
KN-62
Catalog No. A11473 -
CID 2011756
Catalog No. A12416 -
kb NB 142-70
Catalog No. A12423 -
Phenoxybenzamine hydrochloride
Catalog No. A10719 α-adrenergic (AR) 拮抗剂/CaM 抑制剂Phenoxybenzamine hydrochloride是一种细胞可渗透的，非特异性的，不可逆的α-肾上腺素（AR）拮抗剂，也可作为CaM抑制剂。 了解更多 -
CID 755673
Catalog No. A13804 PKD 抑制剂CID755673是一种具有细胞活性的泛PKD1/2/3抑制剂，IC50值分别为180 nM，280nM，以及227 nM。 了解更多 -
KN-93 Phosphate
Catalog No. A14288 CaMKII 抑制剂KN-93 Phosphate是一种有效且特异性的Ca2+/钙调蛋白依赖性蛋白激酶II（CaMKII）抑制剂，Ki为0.37μM，对APK，PKC，MLCK或Ca2+-PDE活性无明显抑制作用。 了解更多 -
K252a
Catalog No. A13897 -
A-484954
Catalog No. A13447 -
KN-92 hydrochloride
Catalog No. A15138 -
KN-92 phosphate
Catalog No. A15139 CaMKII 抑制剂KN-92 phosphate是KN-93的非活性衍生物。KN-93是Ca2+/钙调蛋白依赖性激酶II（CaMKII）的选择性抑制剂，竞争性阻断CaM与激酶的结合（Ki = 370 nM）。 了解更多 -
CID 797718
Catalog No. A13809 PKD1 抑制剂CID797718是CID755673（Adooq目录号A13804）的结构类似物。它是效力降低10倍的PKD1抑制剂，IC50值为7.0+/-0.8 uM。 了解更多 -
CRT-0066101
Catalog No. A16318 PKD 抑制剂CRT-0066101是有效，选择性的蛋白激酶D（PKD）抑制剂；抑制所有PKD同工型（PKD1，PKD3和PKD2的IC50值分别为1、2和2.5 nM）。 了解更多 -
STO-609 acetate
Catalog No. A16345 -
Pitofenone Hydrochloride
Catalog No. A17053 -
Tacrine HCl
Catalog No. A17374 AChE & butyrylcholinesterase inhibitorTacrine is a derivative of aminoacridine that functions as an inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (IC50s = 31 and 26.5 nM, respectively). 了解更多 -
Pralidoxime Iodide
Catalog No. A17526 -
Edrophonium chloride
Catalog No. A17794 acetylcholinesterase inhibitorEdrophonium Chloride, also known as Tensilon, is an acetylcholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. Edrophonium Chloride has also been used as an antidote to curare principles. 了解更多 -
Galanthamine
Catalog No. A12483 AChE inhibitorGalanthamine is a potent acetylcholinesterase (AChE) inhibitor with an IC50 of 500 nM. 了解更多 -
Acetyllovastatin
Catalog No. A19111 AChE inhibitorAcetyllovastatin, a acetate of Lovastatin, presentes a moderate inhibitory effect against the enzyme acetylcholinesterase with an IC50 of 79 μg/mL. Lovastatin has been found to display antifungal activity, and suppresses proliferation of a number of transformed cell lines. 了解更多 -
(R)-Rivastigmine D6 tartrate
Catalog No. A21454 cholinesterase inhibitor(R)-Rivastigmine D6 (tartrate) is the deuterium labeled (R)-Rivastigmine, which is an cholinesterase inhibitor. 了解更多 -
(+)-Phenserine
Catalog No. A20993 cholinesterase noncompetitive inhibitor(+)-Phenserine is a novel selective cholinesterase noncompetitive inhibitor with an IC50 of 45.3 μM. 了解更多
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