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Neuronal Signaling

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Ibuprofen Lysine (NeoProfen)

Catalog No. A10462
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COX-1 抑制剂

Ibuprofen Lysine(Motrin)是一种非甾体抗炎药。了解更多

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Fexofenadine HCl

Catalog No. A11859
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COX 抑制剂/histamine H1 receptor 激动剂

Fexofenadine Hydrochloride是一种抗组胺药，可抑制Cox-1，Cox-2，并且是组胺H1受体激动剂，IC50为246 nM。了解更多

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Xanthohumol

Catalog No. A15919
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COX 抑制剂

Xanthohumol是一种来自啤酒花的烯丙基查尔酮，可抑制COX-1和COX-2活性并显示化学预防作用。了解更多

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Indomethacin (Indocid, Indocin)

Catalog No. A10474
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COX 抑制剂

Indomethacin (Indocid, Indocin)是一种非选择性COX1和COX2抑制剂，IC50分别为0.1 μg/mL和5 μg/mL。吲哚美辛(吲哚满，吲哚满)是一种非甾体抗炎药，通常用于减轻发热、疼痛、僵硬和肿胀。了解更多

Product Citations (3)

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- Reiko Watanabe, .et al. Development of an In Silico Prediction Model for P-glycoprotein Efflux Potential in Brain Capillary Endothelial Cells toward the Prediction of Brain Penetration, J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967
- Azuma T, .et al. Distribution of six anticancer drugs and a variety of other pharmaceuticals, and their sorption onto sediments, in an urban Japanese river, Environ Sci Pollut Res Int, 2017, Aug;24(23):19021-19030 PMID: 28660504
- Azuma T, .et al. Detection of pharmaceuticals and phytochemicals together with their metabolites in hospital effluents in Japan, and their contribution to sewage treatment plant influents, Sci Total Environ, 2016, Apr 1;548-549:189-197 PMID: 26802347
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Meclofenamate Sodium

Catalog No. A12520
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COX 抑制剂

Meclofenamate Sodium是一种双重COX-1/COX-2抑制剂，IC50为40 nM和50 nM。了解更多

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Lornoxicam (Xefo)

Catalog No. A11695
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COX 抑制剂

Lornoxicam (Xefo)是一种非甾体类COX-1/COX-2抑制剂。它是oxicam类的非甾体类抗炎药（NSAID），具有镇痛（缓解疼痛），抗炎和退烧（退烧）特性。了解更多

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(S)-(+)-Flurbiprofen

Catalog No. A12434
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COX 抑制剂

(S)-(+)-Flurbiprofen是一种非选择性的Cox-1和Cox-2抑制剂。了解更多

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- Xing Jin, .et al. Enantioselective analysis of ketoprofen in human saliva by liquid chromatography/tandem mass spectrometry with chiral derivatization, Microchemical Journal, 2018, 143: 280-285
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SC 560

Catalog No. A13023
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COX-1 抑制剂

SC 560是一种COX-1选择性抑制剂，IC50 值为9 nM。可以用作研究COX-1衍生的PG在炎症和疼痛中的作用的药理学工具。了解更多

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Ibuprofen (Advil)

Catalog No. A10461
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COX-1 抑制剂

Ibuprofen (Advil)是一种非甾体抗炎药(NSAID)，靶向COX-1，IC50为13 μM。了解更多

Product Citations (2)

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- Azuma T, .et al. Distribution of six anticancer drugs and a variety of other pharmaceuticals, and their sorption onto sediments, in an urban Japanese river, Environ Sci Pollut Res Int, 2017, Aug;24(23):19021-19030 PMID: 28660504
- Azuma T, .et al. Detection of pharmaceuticals and phytochemicals together with their metabolites in hospital effluents in Japan, and their contribution to sewage treatment plant influents, Sci Total Environ, 2016, Apr 1;548-549:189-197 PMID: 26802347
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Piroxicam (Feldene)

Catalog No. A10736
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COX 抑制剂

Piroxicam (Feldene)是前列腺素合成的有效抑制剂，并且是Cox-1和Cox-2抑制剂。了解更多

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Paradol

Catalog No. A15205
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COX-1 抑制剂

Paradol是几内亚胡椒（Aframomum melegueta）种子的活性风味成分。已发现Paradol具有抗氧化和抗肿瘤的促进作用。了解更多

Product Citations (2)

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- Taurin Hughes, .et al. Inhibition of Escherichia coli ATP synthase by dietary ginger phenolics, Int J Biol Macromol, 2021, Jul 1;182:2130-2143 PMID: 34087308
- Lihan Zhao, .et al. Efficacy based ginger fingerprinting reveals potential antiproliferative analytes for triple negative breast cancer, Sci Rep, 2020, Nov 5;10(1):19182 PMID: 33154433
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Diclofenac sodium

Catalog No. A10304
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COX 抑制剂

Diclofenac Sodium是一种非选择性的COX抑制剂，完整细胞中的COX-1和-2的IC50分别为0.5μg/ml和0.5μg/ml，作用于绵羊COX-1和COX-2， IC50分别为60和220 nM，用作非甾体类抗炎药（NSAID）来减轻疼痛和减轻疼痛肿胀发炎。了解更多

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(-)-Epicatechin

Catalog No. A12043
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COX-1 抑制剂

(-)-Epicatechin是绿茶的天然产物。(-)表儿茶素是cox-1的抑制剂。了解更多

Product Citations (4)

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- A S D'Costa, .et al. Inhibition of starch digestion by flavonoids: Role of flavonoid-amylase binding kinetics, Food Chem, 2020, Oct 1;341(Pt 2):128256 PMID: 33035827
- Mihaela Tudorache, .et al. Phenolic compounds mediate aggregation of water-soluble polysaccharides and change their rheological properties: Effect of different phenolic compounds, Food Hydrocoll, 2019, 97, Dec, 105193
- Md Shajedul Islam, .et al. UV-C irradiation as an alternative disinfection technique: Study of its effect on polyphenols and antioxidant activity of apple juice, Innovative food science & emerging technologies, 2016, v.34 pp. 344-351
- Islam MS, .et al. Effect of UV Irradiation on the Nutritional Quality and Cytotoxicity of Apple Juice, J Agric Food Chem, 2016, Oct 10 PMID: 27632812