购物车 0 ￥ 0.00
微信关注
申请试用装

Neuronal Signaling

29 个项目

每页

设置降序顺序
  1. GW791343 HCl
    Quick View

    GW791343 HCl

    Catalog No. A11107
    Quick View
    P2X7 modulator
    GW791343 HCl充当人P2X7的负变构调节剂（pIC50 = 6.9-7.2）和大鼠P2X7的正变构调节剂。 了解更多
  2. GW791343 trihydrochloride
    Quick View

    GW791343 trihydrochloride

    Catalog No. A21204
    Quick View
    P2X7 allosteric modulator
    GW791343 3Hcl is a P2X7 allosteric modulator; exhibits species-specific activity and acts as a negative allosteric modulator of human P2X7 (pIC50 = 6.9 - 7.2). 了解更多
  3. CCMI
    Quick View

    CCMI

    Catalog No. A21534
    Quick View
    α7 nAChR-positive allosteric modulator
    CCMI is a potent and selective α7 nAChR-positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs. 了解更多
  4. PNU-120596
    Quick View

    PNU-120596

    Catalog No. A11203
    Quick View
    Nicotinic (α7) Receptor Modulator
    PNU-120596是α7神经元烟碱型乙酰胆碱受体的正变构调节剂。 了解更多
  5. Tebanicline hydrochloride
    Quick View

    Tebanicline hydrochloride

    Catalog No. A21918
    Quick View
    nAChR modulator
    Tebanicline hydrochloride (ABT594 hydrochloride) is a nAChR modulator with potent, orally effective analgesic activity. 了解更多
  6. BNC375
    Quick View

    BNC375

    Catalog No. A18503
    Quick View
    α7 nAChR Modulator
    BNC375 is a Potent, Selective, and Orally Available Type I Positive Allosteric Modulator of α7 nAChRs. 了解更多
  7. (-)-(S)-B-973B
    Quick View

    (-)-(S)-B-973B

    Catalog No. A18761
    Quick View
    α7 nAChR modulator
    -)-(S)-B-973B is a potent allosteric agonist and positive allosteric modulator of α7 nAChR, with antinociceptive activity. 了解更多
  8. A-867744
    Quick View

    A-867744

    Catalog No. A11290
    Quick View
    modulator of α7 nAChRs
    A-867744是α7烟碱乙酰胆碱受体的新型正变构调节剂。 了解更多
  9. (Rac)-VU 6008667
    Quick View

    (Rac)-VU 6008667

    Catalog No. A21939
    Quick View
    mAChR M5 negative allosteric modulator
    (Rac)-VU 6008667 is a selective negative allosteric modulator of muscarinic acetylcholine receptor subtype 5 (M5 NAM) (IC50=1.8 μM, pIC50= 5.75), has high CNS penetration. 了解更多
  10. Rapacuronium bromide
    Quick View

    Rapacuronium bromide

    Catalog No. A21119
    Quick View
    mAChR modulator
    Rapacuronium bromide is an allosteric modulator of muscarinic acetylcholine receptor (mAChR). 了解更多
  11. MK7622
    Quick View

    MK7622

    Catalog No. A12835
    Quick View
    M1 调节剂
    MK7622是毒蕈碱M1受体阳性变构调节剂。 了解更多
  12. GNE 0723
    Quick View

    GNE 0723

    Catalog No. A12757
    Quick View
    NMDAR modulator
    GNE 0723 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 21 nM for GluN2A, 7.4 and 6.2 μM for GluN2C and GluN2D, respectively. 了解更多
  13. GLYX-13 (Rapastinel)
    Quick View

    GLYX-13 (Rapastinel)

    Catalog No. A13576
    Quick View
    NMDAR modulator
    GLYX-13 (Rapastinel)是NMDA受体甘氨酸位点的选择性弱部分激动剂。 了解更多
  14. Lorediplon
    Quick View

    Lorediplon

    Catalog No. A13449
    Quick View
    GABAA receptor modulator
    Lorediplon 是一种新型的非苯二氮卓类催眠药，作为GABAA受体调节剂。 了解更多
  15. Indiplon
    Quick View

    Indiplon

    Catalog No. A13769
    Quick View
    GABAA receptor modulator
    Indiplon是吡唑并嘧啶，可作为GABAA受体的高亲和力正变构调节剂，以剂量依赖和可逆的方式增强GABA活化的氯离子电流。 了解更多
  16. CTP354
    Quick View

    CTP354

    Catalog No. A15939
    Quick View
    GABA(A) modulator
    CTP354是一种新型的氘化亚型选择性GABA（A）调节剂。 了解更多
  17. Basmisanil
    Quick View

    Basmisanil

    Catalog No. A21321
    Quick View
    GABAAα5 modulator
    Basmisanil is a highly selective GABAAα5 negative allosteric modulator. 了解更多
  18. NS11394
    Quick View

    NS11394

    Catalog No. A21425
    Quick View
    GABA(A) receptor modulator
    NS11394 is a potent and subtype-selective GABA(A) receptor-positive modulator; possesses a functional efficacy selectivity profile of alpha(5) > alpha(3) > alpha(2) > alpha(1) at GABA(A) alpha subunit-containing receptors. 了解更多
  19. BPN-15606
    Quick View

    BPN-15606

    Catalog No. A18681
    Quick View
    γ-secretase modulator
    BPN-15606 is a highly potent, orally active γ-secretase modulator (GSM), attenuates the production of Aβ42 and Aβ40 by SHSY5Y neuroblastoma cells with IC50 values of 7 nM and 17nM, respectively. 了解更多
  20. NGP-555
    Quick View

    NGP-555

    Catalog No. A17051
    Quick View
    γ-Secretase Modulator
    NGP-555是一种γ-分泌酶调节剂，具有选择性机制，可减少Abeta 42，同时提高较短的Abeta形式，例如Abeta 37和38。 了解更多
  21. gamma-secretase modulator 2
    Quick View

    gamma-secretase modulator 2

    Catalog No. A11427
    Quick View
    Gamma-secretase modulator
    Gamma-secretase modulator 2是γ-secretase调节剂，可用于阿尔兹海默。 了解更多
  22. Flurizan
    Quick View

    Flurizan

    Catalog No. A12433
    Quick View
    gamma-secretase modulator
    Flurizan是一种非甾体抗炎药（NSAID），可抑制γ-分泌酶的活性。 了解更多
  23. E 2012
    Quick View

    E 2012

    Catalog No. A11393
    Quick View
    gamma-secretase modulator
    E 2012是γ-secretase抑制剂。 了解更多
  24. gamma-secretase modulator 3
    Quick View

    gamma-secretase modulator 3

    Catalog No. A15090
    Quick View
    gamma-secretase modulator
    gamma-secretase modulator 3 是γ-分泌酶调节剂。 了解更多
  25. TC-E 5006
    Quick View

    TC-E 5006

    Catalog No. A13217
    Quick View
    Gamma-secretase modulator
    TC-E 5006是一种γ-分泌酶调节剂。在体外（EC50 = 390 nM）和体内降低Aβ42水平。 了解更多
  26. gamma-secretase modulator 1
    Quick View

    gamma-secretase modulator 1

    Catalog No. A11425
    Quick View
    Gamma-secretase modulator
    gamma-secretase modulator 1是γ-分泌酶调节剂，γ-分泌酶调节剂1可用于阿尔茨海默病。 了解更多
  27. Compound W
    Quick View

    Compound W

    Catalog No. A15296
    Quick View
    Gamma-secretase modulator
    Compound W是一种γ-分泌酶抑制剂，已被证明可以降低分泌的Aβ42和Nβ25的水平。 了解更多
  28. CHF5074
    Quick View

    CHF5074

    Catalog No. A16214
    Quick View
    γ-Secretase modulator
    CHF5074是新型的γ-分泌酶调节剂，可减少Aβ42和Aβ40的分泌，IC50分别为3.6和18.4 uM。 了解更多
  29. ARN2966
    Quick View

    ARN2966

    Catalog No. A21016
    Quick View
    APP expression modulator
    ARN2966 is a potent post-transcriptional modulator of APP expression; reduces expression of APP with resultant lower production of Aβ. 了解更多

29 个项目

每页

设置降序顺序
FILTER BY:

Filtering:

  1. 作用机制: Modulator (调节剂) 删除该内容
清除全部

购物选项

分类
  1. β-Amyloid (1)
  2. γ-Secretase (10)
  3. GABA Receptors (5)
  4. NMDA Receptors (2)
  5. mAChR (3)
  6. nAChR (6)
  7. P2X Receptor (2)
联系我们
ChinaChina

Adooq 中国 (南京百鑫德诺生物科技有限公司)

免费电话: 400-025-6535

企业QQ: 400-025-6535

www.adooq.cn

sales@adooq.cn

United StatesUnited States

Adooq Bioscience

Toll Free: (866) 930-6790

Fax: +1-323-606-8156

Email: sales@adooq.com

Not your Region? View all Distributors

溶液配制计算器

分子量计算器

稀释计算器

摩尔浓度计算器

ADOOQ 产品质量保证
Guaranteed product quality, 365 days Unconditional Return & Replacement

We promise all products to perform as described.

立即申请
Get Code
联系我们
查看FAQs

Adooq 公司

产品订购

技术资源

地址

© 2006-2019 AdooQ BioScience （南京百鑫德诺生物科技有限公司）. All Rights Reserved.
苏ICP备14027875号
Accept Payment
Rewards