NF-kB/IkB
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CI994 (Tacedinaline)
Catalog No. A11964 -
Romidepsin (FK228 ,Depsipeptide)
Catalog No. A11920 HDAC 抑制剂Romidepsin (FK228,Depsipeptide)抑制HDAC1和HDAC2,IC50分别为1.6 nM和3.9 nM,但相对较弱地分别抑制HDAC4和HDAC6,IC50值为25 nM和79 nM。 了解更多 -
RGFP966
Catalog No. A13218 -
Resminostat
Catalog No. A12556 HDAC 抑制剂Resminostat,也称为RAS2410,是一种有效的I和II类组蛋白脱乙酰基酶(HDAC)抑制剂。它结合并抑制HDAC,从而导致高度乙酰化的组蛋白的积累。选择性的抑制HDAC1/3/6,IC50为42.5 nM/50.1 nM/71.8 nM,作用于HDAC8效果弱,IC50为877 nM。 了解更多 -
RG2833 (RGFP109)
Catalog No. A13139 -
BRD73954
Catalog No. A15489 -
Resminostat hydrochloride
Catalog No. A15220 HDAC 抑制剂Resminostat hydrochloride是HDAC1/3/6的有效抑制剂(IC50 = 43-72 nM);对HDAC8的效力较低,IC50为877 nM。 了解更多 -
KD 5170
Catalog No. A15354 -
TCS HDAC6 20b
Catalog No. A15387 HDAC6 抑制剂TCS HDAC6 20b是组蛋白脱乙酰基酶6(HDAC6)的选择性抑制剂。与紫杉醇联合抑制HCT116的生长。还抑制雌激素刺激的MCF-7细胞的生长。 了解更多 -
Citarinostat (ACY-241)
Catalog No. A12758 HDAC6 抑制剂ACY-241是HDAC6的新型,选择性和口服抑制剂。对HDAC6和HDAC3的IC50分别为2.6 nM和46 nM。 了解更多 -
ITSA-1
Catalog No. A16127 -
CAY10603
Catalog No. A16431 -
CRA-026440
Catalog No. A12179 -
Valproic acid sodium salt
Catalog No. A10855 HDAC inhibitorValproic acid sodium salt (Sodium Valproate) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. 了解更多 -
JAK/HDAC-IN-1
Catalog No. A13362 JAK2/HDAC dual inhibitorJAK/HDAC-IN-1 is a potent JAK2/HDAC dual inhibitor, exhibits antiproliferative and proapoptotic activities in several hematological cell lines. 了解更多 -
Sodium phenylbutyrate
Catalog No. A16714 HDAC/ER stress inhibitorSodium phenylbutyrate is an inhibitor of HDAC and endoplasmic reticulum (ER) stress, used in cancer and infection research. 了解更多 -
Tubastatin A
Catalog No. A16770 HDAC6 inhibitorTubastatin A is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay, and is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more). 了解更多 -
Givinostat
Catalog No. A21126 HDAC inhibitorGivinostat (ITF-2357) is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. 了解更多 -
Givinostat hydrochloride
Catalog No. A21487 HDAC inhibitorGivinostat hydrochloride (ITF-2357 hydrochloride) is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. 了解更多 -
Nanatinostat
Catalog No. A21625 HDAC inhibitorNanatinostat (CHR-3996) is a potent, class I selective and orally active histone deacetylase (HDAC) inhibitor with an IC50 of 8 nM. 了解更多 -
Belinostat
Catalog No. A21772 HDAC inhibitorBelinostat (PXD101; PX105684) is a potent HDAC inhibitor with an IC50 of 27 nM in HeLa cell extracts. 了解更多 -
HDAC-IN-5
Catalog No. A20972 -
Domatinostat tosylate
Catalog No. A20986 HDAC1 inhibitorDomatinostat tosylate (4SC-202) is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. It also displays inhibitory activity against Lysine specific demethylase 1 (LSD1). 了解更多 -
Bay 11-7821
Catalog No. A11957 E2 ubiquitin conjugating enzyme 抑制剂Bay 11-7821是TNF-α刺激的IκBα磷酸化的不可逆抑制剂。 了解更多 -
IMD 0354
Catalog No. A12837 -
BAY 11-7085
Catalog No. A12470 -
BMS-345541
Catalog No. A12559 -
PS-1145
Catalog No. A12789