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NF-kB/IkB

产品 101 到 131 共 131个

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  1. HDAC-IN-5
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    HDAC-IN-5

    Catalog No. A20972
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    HDAC inhibitor
    HDAC-IN-5 is a histone deacetylase (HDAC) inhibitor. 了解更多
  2. Domatinostat tosylate
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    Domatinostat tosylate

    Catalog No. A20986
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    HDAC1 inhibitor
    Domatinostat tosylate (4SC-202) is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. It also displays inhibitory activity against Lysine specific demethylase 1 (LSD1). 了解更多
  3. Nexturastat A
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    Nexturastat A

    Catalog No. A14032
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    HDAC6 抑制剂
    Nexturastat A是一种芳基脲衍生物，可作为组蛋白脱乙酰基酶6（HDAC6）的有效且高度选择性的抑制剂（IC50 = 5.02+/-0.60 nM）。 了解更多
  4. HPOB
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    HPOB

    Catalog No. A14197
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    HDAC6 抑制剂
    HPOB是组蛋白去乙酰化酶6(HDAC6；IC50 = 56 nM)。 了解更多
  5. Splitomicin
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    Splitomicin

    Catalog No. A14221
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    NAD(+)-dependent histone deacetylase Sir2p 抑制剂
    Splitomicin是一种选择性的NAD(+)-依赖性组蛋白脱乙酰基酶Sir2p抑制剂，IC50为60 uM，在基于细胞的测定中显示出更高的活性。 了解更多
  6. Tasquinimod
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    Tasquinimod

    Catalog No. A12616
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    HDAC4 抑制剂
    Tasquinimod是一种变构抑制HDAC4信号传导的口服活性抗血管生成剂。 了解更多
  7. Santacruzamate A
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    Santacruzamate A

    Catalog No. A14236
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    HDAC 抑制剂
    Santacruzamate A (CAY10683)是一种有效的选择性HDAC抑制剂，对HDAC2的IC50为119 pM，选择性是其他HDAC的3600倍以上。 了解更多
  8. LMK-235
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    LMK-235

    Catalog No. A14341
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    HDAC4/5 抑制剂
    LMK-235是选择性组蛋白脱乙酰基酶(HDAC) 4和HDAC5抑制剂。 了解更多
  9. ST7612AA1
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    ST7612AA1

    Catalog No. A14418
    HDAC 抑制剂
    ST7612AA1是新型的有效HDAC抑制剂，具有潜在的抗癌活性。 了解更多
  10. Domatinostat (4SC-202)
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    Domatinostat (4SC-202)

    Catalog No. A14354
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    HDAC 抑制剂
    4SC-202是生物利用的苯甲酰胺和人I类组蛋白脱乙酰基酶（HDACs）同工酶1、2和3的抑制剂，具有潜在的抗肿瘤活性。 了解更多
  11. TMP 195
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    TMP 195

    Catalog No. A14326
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    HDAC 抑制剂
    TMP195是最有效和选择性的IIa类HDAC抑制剂。 了解更多
  12. UF010
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    UF010

    Catalog No. A15781
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    HADC 抑制剂
    UF010是一种有效的选择性HADC抑制剂，对于HDAC 3、2、1和8分别具有IC50?0.06 uM，0.1 uM，0.5 uM和1.5 uM。它的选择性是其他HDAC的6倍以上。 了解更多
  13. HDAC inhibitor
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    HDAC inhibitor

    Catalog No. A13405
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    HDAC 抑制剂
    N/A 了解更多
  14. SR-4370
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    SR-4370

    Catalog No. A16899
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    HDAC 抑制剂
    SR-4370是HDAC抑制剂。SR-4370对HDAC1，HDAC2和HDAC3的IC50值分别为0.5 uM，0.1 uM和0.06 uM。 了解更多
  15. HDAC8-IN-1
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    HDAC8-IN-1

    Catalog No. A17091
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    HDAC8 抑制剂
    HDAC8-IN-1是一种HDAC8抑制剂，在癌细胞系中的IC50为27.2 nM。 了解更多
  16. Tinostamustine (EDO-S101)
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    Tinostamustine (EDO-S101)

    Catalog No. A18342
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    HDAC inhibitor
    EDO-S101 is a pan HDAC inhibitor; inhibits HDAC1, HDAC2 and HDAC3 with IC50 values of 9, 9 and 25 nM, respectively. 了解更多
  17. SKLB-23bb
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    SKLB-23bb

    Catalog No. A18339
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    HDAC6 inhibitor
    SKLB-23bb is a potent and selective inhibitor for HDAC6 with an IC50 of 17 nM and shows 25-fold and 200-fold selectivity relative to HDAC1 (IC50=422 nM) and HDAC8 (IC50=3398 nM), respectively. 了解更多
  18. Valproic acid
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    Valproic acid

    Catalog No. A17323
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    HDAC inhibitor
    Valproic acid is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2; Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches. 了解更多
  19. Tucidinostat (Chidamide)
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    Tucidinostat (Chidamide)

    Catalog No. A17861
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    HDAC inhibitor
    Tucidinostat is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, less active on HDAC8 and HDAC11 (IC50s, 733 nM, 432 nM, respectively), and shows no effect on HDAC4/5/6/7/9. 了解更多
  20. CM-675
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    CM-675

    Catalog No. A18741
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    PDE5/HDAC-1 inhibitor
    CM-675 is a dual phosphodiesterase 5 (PDE5) and class I histone deacetylases-selective inhibitor, with IC50 values of 114 nM and 673 nM for PDE5 and HDAC1, respectively. CM-675 has potential to treat Alzheimer??s disease. 了解更多
  21. SIS-17
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    SIS-17

    Catalog No. A18463
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    HDAC 11 inhibitor
    SIS17 is a potent and selective HDAC 11 inhibitor with an IC50 value of 0.83 μM. SIS17, is active in cells and inhibited the demyristoylation of a known HDAC11 substrate, serine hydroxymethyl transferase 2, without inhibiting other HDACs. 了解更多
  22. AES-135
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    AES-135

    Catalog No. A19087
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    HDAC inhibitor
    AES-135 is a potent HDAC inhibitor, inhibits HDAC3, HDAC6, HDAC11 with IC50s of 654, 190, and 636 nM, respectively. Anti-tumor activity. 了解更多
  23. MPT0E028
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    MPT0E028

    Catalog No. A18982
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    HDAC inhibitor
    MPT0E028 is an orally active and selective HDAC inhibitor with IC50s of 53.0 nM, 106.2 nM, 29.5 nM for HDAC1, HDAC2 and HDAC6, respectively. 了解更多
  24. SS-208
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    SS-208

    Catalog No. A18952
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    HDAC6 inhibitor
    SS-208 is a selective HDAC6 inhibitor, with an IC50 of 12 nM. SS-208 possesses anti-tumor activity in melanoma. 了解更多
  25. SW-100
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    SW-100

    Catalog No. A18947
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    HDAC6 inhibitor
    SW-100, a selective histone deacetylase 6 (HDAC6) inhibitor with an IC50 of 2.3 nM, shows at least 1000-fold selectivity for HDAC6 relative to all other HDAC isozymes. 了解更多
  26. CHDI-390576
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    CHDI-390576

    Catalog No. A18899
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    HDAC inhibitor
    CHDI-390576, a potent, cell permeable and CNS penetrant class IIa histonedeacetylase (HDAC) inhibitor with IC50s of 54 nM, 60 nM, 31 nM, 50 nM for class IIa HDAC4, HDAC5, HDAC7, HDAC9, respectively, shows >500-fold selectivity over class I HDACs (1, 2, 3) and ~150-fold selectivity over HDAC8 and the class IIb HDAC6 isoform. 了解更多
  27. ACY-775
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    ACY-775

    Catalog No. A12456
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    HDAC6 inhibitor
    ACY-775 is a potent and selective inhibitor of the of histone deacetylase 6 (HDAC6) with an IC50 of 7.5?nM. 了解更多
  28. Remetinostat
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    Remetinostat

    Catalog No. A12149
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    HDAC inhibitor
    Remetinostat (SHP-141) is a hydroxamic acid-based inhibitor of histone deacetylase enzymes (HDAC) which is under development for the treatment of cutaneous T-cell lymphoma. 了解更多
  29. CXD101
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    CXD101

    Catalog No. A12253
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    HDAC inhibitor
    CXD101 is a class I-selective HDAC inhibitor (HDAC1 (IC50, 63 nM), HDAC2 (IC50, 570 nM), HDAC3 (IC50, 550 nM). CXD101 has no activity against HDAC class II. 了解更多
  30. BRD-6929
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    BRD-6929

    Catalog No. A12511
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    HDAC1/HDAC2 inhibitor
    BRD-6929 (Cpd-60) is a brain-penetrant, selective inhibitor of HDAC1 and HDAC2 (IC50=?1 and 8 nM), extracted from patent US2018360927. 了解更多
  31. HDACs/mTOR Inhibitor 1
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    HDACs/mTOR Inhibitor 1

    Catalog No. A13462
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    HDACs/mTOR Inhibitor 1
    HDACs/mTOR Inhibitor 1 is a dual Histone Deacetylases (HDACs) and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies. 了解更多

产品 101 到 131 共 131个

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