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NG52 (Compound 52)是细胞周期调节激酶Cdc28p（IC50 = 7 μM）和相关Pho85p激酶（IC50 = 2 μM）的有效，可渗透细胞，可逆，选择性和ATP兼容的抑制剂。
| In vitro | DMSO | 59 mg/mL (170.12 mM) | |
| Water | Insoluble | ||
| Ethanol | 20 mg/mL (57.66 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.83 mL | 144.17 mL | 288.34 mL |
| 0.5 mM | 5.77 mL | 28.83 mL | 57.67 mL |
| 1 mM | 2.88 mL | 14.42 mL | 28.83 mL |
| 5 mM | 0.58 mL | 2.88 mL | 5.77 mL |
*The above data is based on the productmolecular weight 346.81. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12494 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 346.81 |
| Formula | C16H19ClN6O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 212779-48-1 |
| Synonyms | Compound 52, NG-52, NG 52 |
| SMILES | CC(C)N1C=NC2=C1N=C(N=C2NC3=CC(=CC=C3)Cl)NCCO |
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