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NKY 80是腺苷酸环化酶（AC）的抑制剂。 与AC3和AC2相比，对AC5的亲和力更大（IC50值分别为8.3μM，132μM和1.7 mM）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 43.62 mL | 218.12 mL | 436.24 mL |
| 0.5 mM | 8.72 mL | 43.62 mL | 87.25 mL |
| 1 mM | 4.36 mL | 21.81 mL | 43.62 mL |
| 5 mM | 0.87 mL | 4.36 mL | 8.72 mL |
*The above data is based on the productmolecular weight 229.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13586 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 229.23 |
| Formula | C12H11N3O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 299442-43-6 |
| Synonyms | NKY80, NKY-80 |
| SMILES | C1C(CC(=O)C2=CN=C(N=C21)N)C3=CC=CO3 |
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