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NSC 23766是Rac特异性GEF TrioN和Tiam 1（IC50 = 50 uM）引起的Rac1激活的细胞可渗透性可逆抑制剂。
靶点信息
| Rac GTPase (Cell-free assay) | ||||
| 50 μM |
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.83 mL | 94.16 mL | 188.32 mL |
| 0.5 mM | 3.77 mL | 18.83 mL | 37.66 mL |
| 1 mM | 1.88 mL | 9.42 mL | 18.83 mL |
| 5 mM | 0.38 mL | 1.88 mL | 3.77 mL |
*The above data is based on the productmolecular weight 531. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13975 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 531 |
| Formula | C24H35N7.3HCl |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1177865-17-6 |
| Synonyms | NSC 23766, NSC23766 |
| SMILES | CCN(CC)CCCC(C)NC1=NC(=CC(=N1)NC2=CC3=C(C=C2)N=C(C=C3N)C)C.Cl.Cl.Cl |
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