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SC 23766是Rac1-GEF相互作用的选择性抑制剂。通过Rac特异性鸟嘌呤核苷酸交换因子（GEF）TrioN和Tiam1（IC50为50 μM）阻止Rac1激活，而不影响Cdc42或RhoA激活。
| In vitro | DMSO | Warmed: 92 mg/mL (173.26 mM) | |
| Water | Warmed: 92 mg/mL (173.26 mM) | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.83 mL | 94.17 mL | 188.33 mL |
| 0.5 mM | 3.77 mL | 18.83 mL | 37.67 mL |
| 1 mM | 1.88 mL | 9.42 mL | 18.83 mL |
| 5 mM | 0.38 mL | 1.88 mL | 3.77 mL |
*The above data is based on the productmolecular weight 530.97. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12546 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 530.97 |
| Formula | C24H35N7 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 733767-34-5 |
| Synonyms | NSC-23766, NSC23766 |
| SMILES | CCN(CC)CCCC(C)NC1=NC(=CC(=N1)NC2=CC3=C(C=C(N=C3C=C2)C)N)C |
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