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NVP-ADW742是一种IGF-1R抑制剂，IC50为0.17μM。
靶点信息
| IGF-1R | ||||
| 0.17 μM |
| In vitro | DMSO | Warmed: 9 mg/mL (19.84 mM) | |
| Water | Insoluble | ||
| Ethanol | 3 mg/mL (6.61 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.05 mL | 110.23 mL | 220.46 mL |
| 0.5 mM | 4.41 mL | 22.05 mL | 44.09 mL |
| 1 mM | 2.2 mL | 11.02 mL | 22.05 mL |
| 5 mM | 0.44 mL | 2.2 mL | 4.41 mL |
*The above data is based on the productmolecular weight 453.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10658 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 453.6 |
| Formula | C28H31N5O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 475488-23-4 |
| Synonyms | NVPADW742, ADW742, ADW-742, GSK 552602A |
| SMILES | C1CCN(C1)CC2CC(C2)N3C=C(C4=C3N=CN=C4N)C5=CC(=CC=C5)OCC6=CC=CC=C6 |
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