NVP-BAG956

Name: NVP-BAG956
SKU: A11511

目录号: A11511

PI3K/PDK-1 抑制剂

NVP-BAG956 Chemical Structure

CAS NO. 853910-02-8

NVP-BAG956是一种强效、可逆和ATP竞争性PI3-K/PDK1双激酶抑制剂，对VEGFR 1(IC50 = 2.56 μM)的效力大大降低，对其他15种激酶(IC50 > 10 uM)的活性很小或没有活性。

库存：现货

规格	价格	数量
5 mg	￥ 560.00
10 mg	￥ 980.00
25 mg	￥ 1,960.00
50 mg	￥ 3,360.00

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生物活性

NVP-BAG956是一种强效、可逆和ATP竞争性PI3-K/PDK1双激酶抑制剂，对VEGFR 1(IC50 = 2.56 μM)的效力大大降低，对其他15种激酶(IC50 > 10 uM)的活性很小或没有活性。

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.39 mL	116.96 mL	233.92 mL
0.5 mM	4.68 mL	23.39 mL	46.78 mL
1 mM	2.34 mL	11.7 mL	23.39 mL
5 mM	0.47 mL	2.34 mL	4.68 mL

*The above data is based on the productmolecular weight 427.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11511
作用机制	Inhibitor (抑制剂)
M. Wt	427.5
Formula	C28H21N5
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	853910-02-8
Synonyms	NVP-BAG 956
SMILES	CC1=NC2=CN=C3C=CC(=CC3=C2N1C4=CC=C(C=C4)C(C)(C)C#N)C#CC5=CN=CC=C5