产品详情

生物活性

OG-L002是一种有效的特异性LSD1抑制剂，IC50为20 nM，分别比MAO-B和MAO-A表现出36倍和69倍的选择性。

靶点信息

LSD1 (Cell-free assay)
20 nM

溶解度 *

In vitro (25°C)	DMSO	41 mg/mL (181.99 mM)
	Water	Insoluble
	Ethanol	17 mg/mL (75.45 mM)
In vivo	1% DMSO+30% polyethylene glycol+1% Tween 80	19 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	38.2 mL	191.02 mL	382.04 mL
0.5 mM	7.64 mL	38.2 mL	76.41 mL
1 mM	3.82 mL	19.1 mL	38.2 mL
5 mM	0.76 mL	3.82 mL	7.64 mL

*The above data is based on the productmolecular weight 261.75. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A13246
作用机制	Inhibitor (抑制剂)
M. Wt	261.75
Formula	C15H15NO.HCl
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1357302-64-7
Synonyms	OGL002, OG L002
SMILES	CCOc1cc(ccc1Nc1ncc2c(n1)n(C)c1ccccc1c(=O)n2C)N1CCC(CC1)O