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ORM-10962 is a potent, highly selective sodium-calcium exchanger (NCX) inhibitor, with IC50 values of 67 and 55 nM for the reverse and forward mode inhibition, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.76 mL | 108.8 mL | 217.61 mL |
| 0.5 mM | 4.35 mL | 21.76 mL | 43.52 mL |
| 1 mM | 2.18 mL | 10.88 mL | 21.76 mL |
| 5 mM | 0.44 mL | 2.18 mL | 4.35 mL |
*The above data is based on the productmolecular weight 459.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A19158 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 459.54 |
| Formula | C27H29N3O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 763926-98-3 |
| Synonyms | ORM10962, ORM 10962 |
| SMILES | O=C(NC1=CC=C(OC2=CC=C3C(CCC(C4=CC=CC=C4)O3)=C2)N=C1)CN5CCC(O)CC5 |
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