产品详情

OSU-T315 (ILK-IN-1) is a small Integrin-linked kinase (ILK) inhibitor with an IC50 of 0.6 μM, inhibiting PI3K/AKT signaling by dephosphorylation of AKT-Ser473 and other ILK targets (GSK-3β and myosin light chain).

溶解度 *

In vitro	DMSO	91 mg/mL (170.53 mM)
	Water	<1 mg/mL
	Ethanol	10 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.74 mL	93.7 mL	187.41 mL
0.5 mM	3.75 mL	18.74 mL	37.48 mL
1 mM	1.87 mL	9.37 mL	18.74 mL
5 mM	0.37 mL	1.87 mL	3.75 mL

*The above data is based on the productmolecular weight 533.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A20870
作用机制	Inhibitor (抑制剂)
M. Wt	533.59
Formula	C30H30F3N5O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	2070015-22-2
Synonyms	OSUT315, OSU T315
SMILES	O=C(NC)CCC1=CC(C2=CC=C(C3=CC=C(C(F)(F)F)C=C3)C=C2)=NN1C4=CC=C(N5CCNCC5)C=C4