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Ozarelix是第四代GnRH拮抗剂，诱导激素难治性雄激素受体阴性前列腺癌细胞凋亡，调节死亡受体的表达和活性。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 6.86 mL | 34.3 mL | 68.6 mL |
| 0.5 mM | 1.37 mL | 6.86 mL | 13.72 mL |
| 1 mM | 0.69 mL | 3.43 mL | 6.86 mL |
| 5 mM | 0.14 mL | 0.69 mL | 1.37 mL |
*The above data is based on the productmolecular weight 1457.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12350 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 1457.7 |
| Formula | C72H96ClN17O14 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 295350-45-7 |
| Synonyms | Ac-D-2-Nal-D-4-Cpa-D-3-Pal-Ser-N-Me-Tyr-D-Hci-Nle-Arg-Pro-D-Ala-NH2 |
| SMILES | CCCC[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)N)NC(=O)[C@@H](CCCCNC(=O)N)NC(=O)[C@H](CC2=CC=C(C=C2)O)N(C)C(=O)[C@H](CO)NC(=O)[C@@H](CC3=CN=CC=C3)NC(=O)[C@@H](CC4=CC=C(C=C4)Cl)NC(=O)[C@@H](CC5=CC6=CC=CC=C6C=C5)NC(=O)C |
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