PA-824 (Pretomanid)

Name: PA-824 (Pretomanid)
SKU: A11401

目录号: A11401

Product Citations (2)

PA-824 (Pretomanid) Chemical Structure

CAS NO. 187235-37-6

PA-824 (Pretomanid)是一种实验性抗结核药物，MIC为<1 μg/mL。

库存：现货

规格	价格	数量
5 mg	￥ 420.00
10 mg	￥ 630.00
50 mg	￥ 1,400.00
100 mg	￥ 2,100.00
10mM * 1mL in DMSO	￥ 630.00

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生物活性

PA-824 (Pretomanid)是一种实验性抗结核药物，MIC为<1 μg/mL。

靶点信息

tuberculosis

溶解度 *

In vitro (25°C)	DMSO	64 mg/mL (178.14 mM)
	Water	Insoluble
	Ethanol	14 mg/mL (38.96 mM)
In vivo	0.5% methylcellulose	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.83 mL	139.16 mL	278.32 mL
0.5 mM	5.57 mL	27.83 mL	55.66 mL
1 mM	2.78 mL	13.92 mL	27.83 mL
5 mM	0.56 mL	2.78 mL	5.57 mL

*The above data is based on the productmolecular weight 359.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11401
M. Wt	359.3
Formula	C14H12F3N3O5
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	187235-37-6
Synonyms	PA824
SMILES	C1[C@@H](COC2=NC(=CN21)[N+](=O)[O-])OCC3=CC=C(C=C3)OC(F)(F)F