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PAP-1 (5-(4-Phenoxybutoxy)psoralen) 是一种有效的，选择性的，口服活性的?Kv1.3?阻滞剂 (EC50=2 nM)。PAP-1 以使用依赖性方式阻止 Kv1.3，并通过优先绑定到通道的 C 型灭活状态来起作用。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.54 mL | 142.71 mL | 285.42 mL |
| 0.5 mM | 5.71 mL | 28.54 mL | 57.08 mL |
| 1 mM | 2.85 mL | 14.27 mL | 28.54 mL |
| 5 mM | 0.57 mL | 2.85 mL | 5.71 mL |
*The above data is based on the productmolecular weight 350.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11521 |
|---|---|
| 作用机制 | Blocker (阻断剂) |
| M. Wt | 350.36 |
| Formula | C21H18O5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 870653-45-5 |
| SMILES | C1=CC=C(C=C1)OCCCCOC2=C3C=CC(=O)OC3=CC4=C2C=CO4 |
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