PD 123319 ditrifluoroacetate

Name: PD 123319 ditrifluoroacetate
SKU: A13201

目录号: A13201

angiotensin AT2 receptor 拮抗剂

Product Citations (1)

PD 123319 ditrifluoroacetate Chemical Structure

CAS NO. 130663-39-7

PD 123319 ditrifluoroacetate是一种有效的，选择性的非肽血管紧张素AT2受体拮抗剂。大鼠肾上腺组织和大脑的IC50值分别为34和210 nM。

库存：现货

规格	价格	数量
10 mg	￥ 840.00
25 mg	￥ 1,680.00
50 mg	￥ 2,800.00
100 mg	￥ 4,900.00
10mM * 1mL in DMSO	￥ 980.00

或

添加到收藏

产品仅用于科学研究，不针对患者销售，望谅解.

产品详情

生物活性

PD 123319 ditrifluoroacetate是一种有效的，选择性的非肽血管紧张素AT2受体拮抗剂。大鼠肾上腺组织和大脑的IC50值分别为34和210 nM。

靶点信息

AT2 receptor
34 nM

溶解度 *

In vitro (25°C)	DMSO	87 mg/mL (171.05 mM)
	Water	87 mg/mL (171.05 mM)
	Ethanol	87 mg/mL (171.05 mM)
In vivo	Saline	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	13.57 mL	67.87 mL	135.75 mL
0.5 mM	2.71 mL	13.57 mL	27.15 mL
1 mM	1.36 mL	6.79 mL	13.57 mL
5 mM	0.27 mL	1.36 mL	2.71 mL

*The above data is based on the productmolecular weight 736.67. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A13201
作用机制	Antagonist (拮抗剂)
M. Wt	736.67
Formula	C31H32N4O3.2CF3CO2H
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	130663-39-7
Synonyms	PD123319, PD-123319
SMILES	CC1=C(C=CC(=C1)CN2C=NC3=C2C[C@H](N(C3)C(=O)C(C4=CC=CC=C4)C5=CC=CC=C5)C(=O)O)N(C)C