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PDK1 inhibitor，强效，ATP竞争性和选择性双重PI3K和PDPK1抑制剂（PDK1和p-T308-PKB抑制的IC50值分别为34 nM和94 nM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.7 mL | 118.52 mL | 237.03 mL |
| 0.5 mM | 4.74 mL | 23.7 mL | 47.41 mL |
| 1 mM | 2.37 mL | 11.85 mL | 23.7 mL |
| 5 mM | 0.47 mL | 2.37 mL | 4.74 mL |
*The above data is based on the productmolecular weight 421.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16185 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 421.88 |
| Formula | C25H15N5.HCl |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 853909-77-0 |
| SMILES | C1=CC(=CN=C1)C#CC2=CC3=C4C(=CN=C3C=C2)N=CN4C5=CC=C(C=C5)CC#N.Cl |
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