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Pemetrexed disodium (Alimta)

Pemetrexed disodium (Alimta)

Name: Pemetrexed disodium (Alimta)
SKU: A10707

目录号: A10707

Pemetrexed disodium (Alimta) Chemical Structure

CAS NO. 150399-23-8

Pemetrexed disodium (Alimta)是一种新型抗叶酸和抗代谢药物，作用于TS，DHFR和GARFT。

库存：现货

规格	价格	数量
10 mg	￥ 280.00
50 mg	￥ 385.00
100 mg	￥ 560.00
200 mg	￥ 910.00

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生物活性

Pemetrexed disodium (Alimta)是一种新型抗叶酸和抗代谢药物，作用于TS，DHFR和GARFT。

靶点信息

TS (Cell-free assay)	DHFR (Cell-free assay)	GARFT (Cell-free assay)
1.3 nM(Ki)	7.2 nM(Ki)	65 nM(Ki)

溶解度 *

In vitro (25°C)	DMSO	Insoluble
	Water	87 mg/mL (184.56 mM)
	Ethanol	Insoluble
In vivo	Saline	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.21 mL	106.07 mL	212.13 mL
0.5 mM	4.24 mL	21.21 mL	42.43 mL
1 mM	2.12 mL	10.61 mL	21.21 mL
5 mM	0.42 mL	2.12 mL	4.24 mL

*The above data is based on the productmolecular weight 471.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10707
M. Wt	471.4
Formula	C20H19N5Na2O6
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	150399-23-8
Synonyms	LY-231514, LY231514
SMILES	C1=CC(=CC=C1CCC2=CNC3=C2C(=O)N=C(N3)N)C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-].[Na+].[Na+]