产品详情
Pemetrexed disodium hemipenta hydrate是TS,DHFR和GARFT的新型抗叶酸和抗代谢药,Ki分别为1.3 nM,7.2 nM和65 nM。
靶点信息
TS | TS | DHFR | DHFR | GARFT |
1.3 nM | 1.3 nM(Ki) | 7.2 nM | 7.2 nM(Ki) | 65 nM(Ki) |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 21.35 mL | 106.74 mL | 213.48 mL |
0.5 mM | 4.27 mL | 21.35 mL | 42.7 mL |
1 mM | 2.13 mL | 10.67 mL | 21.35 mL |
5 mM | 0.43 mL | 2.13 mL | 4.27 mL |
*The above data is based on the productmolecular weight 468.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A15207 |
---|---|
M. Wt | 468.42 |
Formula | C20H23N5NaO7+ |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 357166-30-4 |
Synonyms | Pemetrexed sodium hydrate (1:2:2.5) |
SMILES | C1=CC(=CC=C1CCC2=CNC3=C2C(=O)N=C(N3)N)C(=O)NC(CCC(=O)[O-])C(=O)[O-].C1=CC(=CC=C1CCC2=CNC3=C2C(=O)N=C(N3)N)C(=O)NC(CCC(=O)[O-])C(=O)[O-].O.O.O.O.O.[Na+].[Na+].[Na+].[Na+] |
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