Pemetrexed

目录号: A12668

DHFR 抑制剂

Pemetrexed

Pemetrexed Chemical Structure

CAS NO. 137281-23-3

Pemetrexed 是一种具有多个靶标的新型抗叶酸药。作用于TS,DHFR和GARFT,Ki分别为1.3 nM,7.2 nM 和 65 nM。

库存: 现货

规格 价格 数量
50 mg
¥ 385.00
100 mg
¥ 700.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Pemetrexed 是一种具有多个靶标的新型抗叶酸药。作用于TS,DHFR和GARFT,Ki分别为1.3 nM,7.2 nM 和 65 nM。
In vitro DMSO Insoluble
Water Warmed: 93 mg/mL (180.09 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.4 mL 116.98 mL 233.97 mL
0.5 mM 4.68 mL 23.4 mL 46.79 mL
1 mM 2.34 mL 11.7 mL 23.4 mL
5 mM 0.47 mL 2.34 mL 4.68 mL

*The above data is based on the productmolecular weight 427.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12668
作用机制 Inhibitor (抑制剂)
M. Wt 427.41
Formula C20H21N5O6
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 137281-23-3
SMILES NC1=Nc2[nH]cc(CCc3ccc(cc3)C(=O)N[C@@H](CCC(=O)O)C(=O)O)c2C(=O)N1

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