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PF-04217903 methanesulfonate是一种选择性ATP竞争性c-Met抑制剂，IC50为4.8 nM，易致癌突变（对Y1230C突变体无活性）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.35 mL | 106.73 mL | 213.45 mL |
| 0.5 mM | 4.27 mL | 21.35 mL | 42.69 mL |
| 1 mM | 2.13 mL | 10.67 mL | 21.35 mL |
| 5 mM | 0.43 mL | 2.13 mL | 4.27 mL |
*The above data is based on the productmolecular weight 468.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15208 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 468.49 |
| Formula | C20H20N8O4S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 956906-93-7 |
| Synonyms | PF04217903 methanesulfonate, PF 04217903 methanesulfonate |
| SMILES | CS(=O)(=O)O.C1=CC2=C(C=CC(=C2)CN3C4=NC(=CN=C4N=N3)C5=CN(N=C5)CCO)N=C1 |
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