PF 4981517

Name: PF 4981517
SKU: A12544

目录号: A12544

CYP3A4 抑制剂

PF 4981517 Chemical Structure

CAS NO. 1390637-82-7

PF 4981517是一种有效且选择性的CYP3A4抑制剂（CYP3A4，CYP3A5和CYP3A7的IC50值分别为0.03、17和70 μM）。

库存：现货

规格	价格	数量
5 mg	￥ 560.00
10 mg	￥ 980.00
25 mg	￥ 1,960.00
50 mg	￥ 3,500.00
10mM * 1mL in DMSO	￥ 924.00

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生物活性

PF 4981517是一种有效且选择性的CYP3A4抑制剂（CYP3A4，CYP3A5和CYP3A7的IC50值分别为0.03、17和70 μM）。

靶点信息

CYP3A4
30 nM

溶解度 *

In vitro	DMSO	85 mg/mL (186.16 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.9 mL	109.51 mL	219.01 mL
0.5 mM	4.38 mL	21.9 mL	43.8 mL
1 mM	2.19 mL	10.95 mL	21.9 mL
5 mM	0.44 mL	2.19 mL	4.38 mL

*The above data is based on the productmolecular weight 456.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12544
作用机制	Inhibitor (抑制剂)
M. Wt	456.59
Formula	C26H32N8
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1390637-82-7
Synonyms	PF4981517, PF-4981517
SMILES	CC1=CC=C(C=C1)C2=C(C=NN2C)C3=NN(C4=C3C(=NC=N4)N5CC[C@@H](C5)N6CCCCC6)C