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PF-562271 hydrochloride is a potent, ATP-competitive and reversible FAK and Pyk2 kinase inhibitor with IC50s of 1.5 nM and 13 nM, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.38 mL | 91.92 mL | 183.84 mL |
| 0.5 mM | 3.68 mL | 18.38 mL | 36.77 mL |
| 1 mM | 1.84 mL | 9.19 mL | 18.38 mL |
| 5 mM | 0.37 mL | 1.84 mL | 3.68 mL |
*The above data is based on the productmolecular weight 543.95. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A22370 |
|---|---|
| M. Wt | 543.95 |
| Formula | C21H21ClF3N7O3S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 2 years |
| CAS No. | 939791-41-0 |
| Synonyms | PF562271 hydrochloride,PF 562271 hydrochloride |
| SMILES | CS(=O)(N(C1=NC=CC=C1CNC2=NC(NC3=CC4=C(NC(C4)=O)C=C3)=NC=C2C(F)(F)F)C)=O.[H]Cl |
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