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PHT-427是一种新型的Akt/磷脂酰肌醇依赖性蛋白激酶1 pleckstrin同源域抑制剂。
靶点信息
| Akt | PDK-1 | |||
| 2.7 μM(Ki) | 5.2 μM(Ki) |
| In vitro (25°C) | DMSO | 75 mg/mL (183.1 mM) | |
| Water | Insoluble | ||
| Ethanol | 55 mg/mL (134.27 mM) | ||
| In vivo | 5% DMSO+95% Corn oil | 4 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.41 mL | 122.07 mL | 244.14 mL |
| 0.5 mM | 4.88 mL | 24.41 mL | 48.83 mL |
| 1 mM | 2.44 mL | 12.21 mL | 24.41 mL |
| 5 mM | 0.49 mL | 2.44 mL | 4.88 mL |
*The above data is based on the productmolecular weight 409.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11032 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 409.6 |
| Formula | C20H31N3O2S2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1191951-57-1 |
| Synonyms | PHT427 |
| SMILES | CCCCCCCCCCCCC1=CC=C(C=C1)S(=O)(=O)NC2=NN=CS2 |
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